Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL069061-03
Application #
6787697
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Program Officer
Goldman, Stephen
Project Start
2002-09-30
Project End
2006-08-31
Budget Start
2004-09-01
Budget End
2005-08-31
Support Year
3
Fiscal Year
2004
Total Cost
$313,000
Indirect Cost
Name
New York Medical College
Department
Pathology
Type
Schools of Medicine
DUNS #
041907486
City
Valhalla
State
NY
Country
United States
Zip Code
10595
Chen, Yu-Jung; Quilley, John (2008) Fenofibrate treatment of diabetic rats reduces nitrosative stress, renal cyclooxygenase-2 expression, and enhanced renal prostaglandin release. J Pharmacol Exp Ther 324:658-63
Zhao, Hong; Guan, Qizhi; Smith, Carolyn J et al. (2008) Increased phosphodiesterase 3A/4B expression after angioplasty and the effect on VASP phosphorylation. Eur J Pharmacol 590:29-35
Chen, Yu-Jung; Li, Jing; Quilley, John (2008) Deficient renal 20-HETE release in the diabetic rat is not the result of oxidative stress. Am J Physiol Heart Circ Physiol 294:H2305-12
Zhao, Hong; Quilley, John; Montrose, David C et al. (2007) Differential effects of phosphodiesterase PDE-3/PDE-4-specific inhibitors on vasoconstriction and cAMP-dependent vasorelaxation following balloon angioplasty. Am J Physiol Heart Circ Physiol 292:H2973-81
Chen, Yu-Jung; Li, Jing; Quilley, John (2006) Effect of inhibition of nitric oxide synthase on renal cyclooxygenase in the diabetic rat. Eur J Pharmacol 541:80-6
Takimoto, Eiki; Champion, Hunter C; Belardi, Diego et al. (2005) cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism. Circ Res 96:100-9
Li, Jing; Chen, Yu-Jung; Quilley, John (2005) Effect of tempol on renal cyclooxygenase expression and activity in experimental diabetes in the rat. J Pharmacol Exp Ther 314:818-24