Blood pressure (BP) control in the U.S. is poor despite six sets of guidelines generated over the last 30 years. Poor adherence to guidelines may be due to inadequate systems to track and monitor patients and inadequate therapy adjustments by physicians. While various strategies exist to assist physicians with improving guideline adherence and achieving better BP control, a consistently effective approach to solving the problem has not been found. The long-range goal of the principal investigator is to develop and evaluate collaborative relationships between physicians and pharmacists that improve pharmaco-therapy. This will be a five-year, multi-center, study to evaluate the impact of physician/pharmacist collaborative teams on adherence to hypertension guidelines (JNC-VI) in six community-based family practice sites. There will be two study phases. Phase I comprises a needs assessment to identify barriers to guideline adherence and design intervention implementation refinement strategies. Phase II will be a prospective, randomized trial to assess the impact of physician/pharmacist collaborative teams on hypertension guideline adherence and BP control.
The specific aims of Phase I are to: 1) identify the scope and nature of physician and patient variables that may contribute to poor guideline adherence and 2) to refine the intervention implementation strategy and design tools for assessing guideline adherence and barriers to adherence.
The specific aims of Phase II are: 1) to determine if there is a change in guideline adherence and knowledge of hypertension when physicians are involved in physician/pharmacist teams and 2) to determine if physician/pharmacist teams can achieve better BP control compared to usual care. We expect that the improvement in guideline adherence and reduction in BP with this intervention will significantly impact patients with hypertension. Because there are more than 37 million Americans with uncontrolled hypertension, this model has to potential to become an important strategy to help achieve the BP goals for Healthy People 2010. ? ?

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
1R01HL070740-01A1
Application #
6605046
Study Section
Special Emphasis Panel (ZRG1-SNEM-4 (01))
Program Officer
Einhorn, Paula
Project Start
2003-08-01
Project End
2008-07-31
Budget Start
2003-08-01
Budget End
2004-07-31
Support Year
1
Fiscal Year
2003
Total Cost
$674,010
Indirect Cost
Name
University of Iowa
Department
Other Health Professions
Type
Schools of Pharmacy
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242
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Chen, Ziqian; Ernst, Michael E; Ardery, Gail et al. (2013) Physician-pharmacist co-management and 24-hour blood pressure control. J Clin Hypertens (Greenwich) 15:337-43
Kulchaitanaroaj, Puttarin; Brooks, John M; Ardery, Gail et al. (2012) Incremental costs associated with physician and pharmacist collaboration to improve blood pressure control. Pharmacotherapy 32:772-80
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Carter, Barry L; Rogers, Meaghan; Daly, Jeanette et al. (2009) The potency of team-based care interventions for hypertension: a meta-analysis. Arch Intern Med 169:1748-55
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Carter, Barry L; Sica, Domenic A (2007) Strategies to improve the cardiovascular risk profile of thiazide-type diuretics as used in the management of hypertension. Expert Opin Drug Saf 6:583-94
Ardery, Gail; Carter, Barry L; Milchak, Jessica L et al. (2007) Explicit and implicit evaluation of physician adherence to hypertension guidelines. J Clin Hypertens (Greenwich) 9:113-9

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