This is an application for an administrative supplement in response to PA-20-222: Research Supplement to Promote Diversity in Health-Related Research. This application requests funds to support Sebastian Pace. Mr. Pace is an under-represented minority graduate student who recently finished coursework and is beginning his dissertation research in Dr. Brent Myers's laboratory at Colorado State University where he is co-mentored by Dr. Shane Hentges. The parent award examines the role of a prefrontal cortex-to-brainstem neurocircuit that may prevent the cardiovascular consequences of chronic stress. This supplemental application compliments these studies to determine both the prefrontal innervation of distinct and opposing cell groups in the brainstem as well as potential sex differences in this organization. This experience will be valuable training for Mr. Pace in a number of new techniques and conceptual approaches to further his career in health-related research.

Public Health Relevance

This administrative supplement will be used to support the training of an outstanding minority scientist. The proposed project will determine the sex-specific neurocircuitry of cortical inputs to a cardiovascular regulatory region of the brainstem. These studies will support a larger project investigating potential targets for therapeutic intervention to treat stress-related cardiovascular dysfunction.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
3R01HL150559-02S1
Application #
10260200
Study Section
Neuroendocrinology, Neuroimmunology, Rhythms and Sleep Study Section (NNRS)
Program Officer
OH, Youngsuk
Project Start
2019-12-16
Project End
2023-11-30
Budget Start
2021-01-20
Budget End
2021-11-30
Support Year
2
Fiscal Year
2021
Total Cost
Indirect Cost
Name
Colorado State University-Fort Collins
Department
Other Basic Sciences
Type
Graduate Schools
DUNS #
785979618
City
Fort Collins
State
CO
Country
United States
Zip Code
80523