A broad-based coalition of stakeholders has collaborated to reduce excess antibiotic use in Colorado by developing and disseminating clinical practice guidelines and practice profiles to 2600 primary care physicians throughout the state. Whether, how much and what type of public and patient education to employ on large-scale efforts to decrease unnecessary antibiotic use is not known. The Minimizing Antibiotic Resistance in Colorado (MARC) Project is designed to evaluate the independent and combined marginal impact of two common mechanisms of public and patient education in clinician prescribing behavior: 1) household and office-based materials, and 2) mass media (television, radio, newsprint, web site). The following specific aims will examine the processes and outcomes of care related to each intervention strategy. Results from this project will inform state and federal efforts to improve ambulatory antibiotic prescribing practices.
Specific Aim I A: Develop and implement community educational interventions using (1) household and office-based materials, and (2) mass media.
Specific Aim I B: Measure and assess changes in antibiotic prescription rates for pharyngitis in children, and bronchitis in adults, using commercial MCO and Medicaid administrative data from physician practices.
Specific Aim II A: Conduct household surveys in and outside the intervention communities to measure the impact of each education strategy on public knowledge, attitudes, behavior and self- efficacy.
Specific Aim II B: Conduct a clinician judgment analysis to measure the impact of each education strategy on clinician decision making and empowerment relating to episodes of care for pharyngitis and bronchitis.
Specific Aim III A: Conduct a survey of patients and parents to measure the impact of decreased antibiotic use on duration of illness and satisfaction with care, for children with pharyngitis and adults with bronchitis.
Specific Aim III B: Using active surveillance data from the Colorado Department of Public Health and Environment (CDPHE), compare the incidence of invasive penicillin-resistant S. pneumoniae infections in and outside the intervention communities.
Specific Aim III C: Conduct a net-cost analysis of the different levels of community education.

Agency
National Institute of Health (NIH)
Institute
Agency for Healthcare Research and Quality (AHRQ)
Type
Research Project (R01)
Project #
5R01HS013001-02
Application #
6538196
Study Section
Special Emphasis Panel (ZHS1-HSRD-A (04))
Program Officer
Borotkanics, Robert
Project Start
2001-07-01
Project End
2005-06-30
Budget Start
2002-07-01
Budget End
2003-06-30
Support Year
2
Fiscal Year
2002
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Wigton, Robert S; Darr, Carol A; Corbett, Kitty K et al. (2008) How do community practitioners decide whether to prescribe antibiotics for acute respiratory tract infections? J Gen Intern Med 23:1615-20
Gonzales, Ralph; Corbett, Kitty K; Wong, Shale et al. (2008) ""Get smart Colorado"": impact of a mass media campaign to improve community antibiotic use. Med Care 46:597-605
Gonzales, Ralph; Corbett, Kitty K; Leeman-Castillo, Bonnie A et al. (2005) The ""minimizing antibiotic resistance in Colorado"" project: impact of patient education in improving antibiotic use in private office practices. Health Serv Res 40:101-16