A key prerequisite for high-quality healthcare delivery is effective communication within and across healthcare settings. However, communication can be hampered by the pervasive use of abbreviations in clinical notes. Clinicians use abbreviations to save time during documentation. While abbreviations may seem unambiguous to their authors, they often cause confusion to other readers, including healthcare providers, patients, and natural language processing (NLP) systems attempting to extract clinical terms from text. While the understanding that abbreviations can cause errors is widespread, few have deployed pragmatic solutions for this important problem. The proposed project will develop, evaluate, and share a systematic approach to Clinical Abbreviation Recognition and Disambiguation (CARD), and in doing so substantially aims to benefit existing NLP systems and to improve computer-based documentation systems by reducing ambiguities in electronic records in real-time. The study includes the following five Specific Aims: 1) Develop automated methods to detect abbreviations and their senses from clinical text corpora and build a comprehensive knowledge base of clinical abbreviations;2) Develop and evaluate three automated word sense disambiguation (WSD) classifiers, and establish methods to combine those classifiers to maximize both their performance and coverage;3) Develop the CARD system, and demonstrate its effectiveness by integrating it with two established NLP systems (MedLEE and KnowledgeMap);4) Integrate CARD with an institutional clinical documentation system (Vanderbilt's StarNotes) and evaluate its ability to expand abbreviations in real-time as clinicians generate records;5) Distribute the CARD knowledge base and software for non-commercial uses.

Public Health Relevance

Abbreviations are widely used throughout all types of clinical documents and they cause confusion to both healthcare providers and patients and limit effective communications within and across care settings. This proposed study will develop informatics methods to automatically detect abbreviations and their possible meanings from large clinical text and to disambiguate abbreviations that have multiple meanings. We will also integrate those methods with clinical documentation systems so that abbreviations will be expanded in real-time when physicians entering clinical notes, thus to improve the quality of health records.

Agency
National Institute of Health (NIH)
Institute
National Library of Medicine (NLM)
Type
Research Project (R01)
Project #
1R01LM010681-01
Application #
7866149
Study Section
Biomedical Library and Informatics Review Committee (BLR)
Program Officer
Sim, Hua-Chuan
Project Start
2010-05-31
Project End
2013-05-30
Budget Start
2010-05-31
Budget End
2011-05-30
Support Year
1
Fiscal Year
2010
Total Cost
$387,500
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
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