: Eliminating racial/ethnic disparities in health and health care is a national priority, and obesity is a prime target. During the last 30 years in the U.S., the prevalence of obesity among children has dramatically increased, sparing no age group. By the preschool years, racial/ethnic disparities in obesity prevalence are already present, suggesting that disparities in childhood obesity prevalence have their origins in the earliest stages of life. Several risk factors during pregnancy, infancy, and early childhood have been found to be associated with the development of obesity. However, few studies have examined racial/ethnic differences in these prenatal and early childhood risk factors for childhood obesity. It is possible that racial/ethnic differences in early life risk factors for obesity might contribute to the high prevalence of obesity among minority preschool age children and beyond. In addition, psychosocial and societal stressors, prevalent in racial/ethnic minority populations, may lead to physiologic processes that increase obesity risk. Maternal stress, experiences of racism and interpersonal violence remain unexplored as contributors to childhood obesity and its risk factors. The overall goal of this study is to use both quantitative and qualitative methods to study racial/ethnic disparities in early life risk factors for childhood obesity. In the quantitative phase of this project, we will study African-American, Hispanic, and white children who are participants of two, ongoing, NIH-funded, cohort studies of pregnant women and their children in Massachusetts: Project Viva and Project ACCESS (Asthma Coalition on Community, Environment, and Social Stress). Together, these cohorts comprise over 2000 racially, ethnically, and socioeconomically diverse mother-infant pairs. In the qualitative phase of this study, we will enhance our quantitative findings by conducting focus group discussions with racial/ethnic minority women during pregnancy, infancy, and early childhood to further probe the underlying reasons for disparities in early life obesity-related risk factors. The members of the interdisciplinary research team are well qualified to conduct the study, as they have pioneered epidemiologic studies on the origins of obesity during pregnancy and the postpartum period, and have extensive experience in examining racial/ethnic disparities in health and health care. With its innovative design, foundation in evidence, and feasibility, the proposed study may very well open up new avenues for interventions to prevent childhood obesity in the very segments of the US population who need it most.

Public Health Relevance

Childhood obesity is prevalent, of consequence, and has its origins in the earliest stages of life. Racial/ethnic minority children bear a disproportionate share of the burden of obesity and its related co-morbidities. The proposed project will study racial/ethnic disparities in early life risk factors for childhood obesity, including those during pregnancy, infancy, and early childhood, and may help inform the design of clinical and public health interventions to reduce disparities in childhood obesity and its complications.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Research Project (R01)
Project #
5R01MD003963-04
Application #
8260124
Study Section
Special Emphasis Panel (ZMD1-PA (R4))
Program Officer
Alvidrez, Jennifer L
Project Start
2009-09-25
Project End
2013-04-30
Budget Start
2012-05-01
Budget End
2013-04-30
Support Year
4
Fiscal Year
2012
Total Cost
$405,805
Indirect Cost
$97,885
Name
Harvard Pilgrim Health Care, Inc.
Department
Type
DUNS #
071721088
City
Boston
State
MA
Country
United States
Zip Code
02215
Chiu, Yueh-Hsiu Mathilda; Hsu, Hsiao-Hsien Leon; Wilson, Ander et al. (2017) Prenatal particulate air pollution exposure and body composition in urban preschool children: Examining sensitive windows and sex-specific associations. Environ Res 158:798-805
Peña, Michelle-Marie; Rifas-Shiman, Sheryl L; Gillman, Matthew W et al. (2016) Racial/Ethnic and Socio-Contextual Correlates of Chronic Sleep Curtailment in Childhood. Sleep 39:1653-61
Criss, Shaniece; Woo Baidal, Jennifer A; Goldman, Roberta E et al. (2015) The Role of Health Information Sources in Decision-Making Among Hispanic Mothers During Their Children's First 1000 Days of Life. Matern Child Health J 19:2536-43
Woo Baidal, Jennifer A; Criss, Shaniece; Goldman, Roberta E et al. (2015) Reducing Hispanic children's obesity risk factors in the first 1000 days of life: a qualitative analysis. J Obes 2015:945918
de Hoog, Marieke L A; Kleinman, Ken P; Gillman, Matthew W et al. (2014) Racial/ethnic and immigrant differences in early childhood diet quality. Public Health Nutr 17:1308-17
Taveras, Elsie M; Gillman, Matthew W; Kleinman, Ken P et al. (2013) Reducing racial/ethnic disparities in childhood obesity: the role of early life risk factors. JAMA Pediatr 167:731-8
Fiechtner, Lauren; Block, Jason; Duncan, Dustin T et al. (2013) Proximity to supermarkets associated with higher body mass index among overweight and obese preschool-age children. Prev Med 56:218-21
Benjamin Neelon, Sara E; Reyes-Morales, Hortensia; Haines, Jess et al. (2013) Nutritional quality of foods and beverages on child-care centre menus in Mexico. Public Health Nutr 16:2014-22
Sonneville, Kendrin R; Rifas-Shiman, Sheryl L; Kleinman, Ken P et al. (2012) Associations of obesogenic behaviors in mothers and obese children participating in a randomized trial. Obesity (Silver Spring) 20:1449-54
Bottino, Clement J; Rifas-Shiman, Sheryl L; Kleinman, Ken P et al. (2012) The association of urbanicity with infant sleep duration. Health Place 18:1000-5

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