Depression for ethnic minorities is a common, disabling condition with documented disparities in access, quality and outcomes of care, particularly in primary care, which is a main treatment setting for ethnic minority groups. Quality improvement programs in primary care can reduce disparities in depression outcomes but are seldom available in vulnerable communities. The proposed project will use the data, partnership infrastructure, and research approach of """"""""Community Partners in Care"""""""" (CPIC)-augmented by new collection of qualitative data-to shed light on the pathways by which health and social disparities can be reduced, as well as to illuminate how scientific research can inform policy development for neighborhood-focused health improvement. CPIC is a community-partnered randomized trial comparing the effectiveness of a community engagement and planning (CEP) intervention that activates multi-agency networks versus a technical assistance model for individual agencies, in implementing evidence-based interventions for depression in two under-resourced communities of color in Los Angeles. Analyses of 6-month client outcomes indicate that the CEP intervention, relative to technical assistance, led to improved mental wellness and physical health and reduced prevalence of poor mental health, risk factors for homelessness, and missed work days due to health. CPIC was implemented with community participatory co-leadership, including leaders'self-reflection on racism and social justice. The proposed investigators are original developers of CPIC. The proposed new secondary analyses and new qualitative data collection will clarify pathways for intervention effects on key subgroups (each community, African Americans and Latinos, men and women, homeless);develop explanatory models using mixed-methods;document intervention implementation for these groups;and explore the applicability and generalizability of the CPIC approach for a new Los Angeles County neighborhood-based health improvement initiative. The public health significance of the research is enhanced by the fact that it will be conducted entirely in partnership with leaders and members from the affected communities using a Community Partnered Participatory Research approach, which promotes equality and collaborative responsibility for all phases of work. Through that model's focus on equity and self-reflection among all leaders on the impact of racism, the proposed project will serve as an early example of a fourth-generation approach to addressing health disparities, which combines comprehensive intervention models and research strategy that incorporates the community context for racial and ethnic differences and the interactions in partnered leadership. .

Public Health Relevance

The proposed work will have public health impact in three ways: (1) it will shed light on pathways to reducing mental health and social disparities among specific subgroups (most notably African Americans, Latinos, gender groups, the homeless, and uninsured) who benefited from a community-partnered intervention to improve depression care in underserved communities;(2) it will explore the generalizability and replicability of the Community Partners in Care model to the implementation of a neighborhood health initiative in Los Angeles to reduce mental health and social disparities;and, more broadly, (3) it will serve as a model for how scientific research can be incorporated into policy in models for neighborhood-based initiatives aimed at reducing disparities in underserved communities of color.

National Institute of Health (NIH)
National Institute on Minority Health and Health Disparities (NIMHD)
Research Project (R01)
Project #
Application #
Study Section
Special Emphasis Panel (ZMD1-DRI (01))
Program Officer
Alvidrez, Jennifer L
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Rand Corporation
Santa Monica
United States
Zip Code
Choi, Kristen R; Sherbourne, Cathy; Tang, Lingqi et al. (2018) A Comparative Effectiveness Trial of Depression Collaborative Care: Subanalysis of Comorbid Anxiety. West J Nurs Res :193945918800333
Castillo, Enrico G; Shaner, Roderick; Tang, Lingqi et al. (2018) Improving Depression Care for Adults With Serious Mental Illness in Underresourced Areas: Community Coalitions Versus Technical Support. Psychiatr Serv 69:195-203
Khodyakov, Dmitry; Williams, Pluscedia; Bromley, Elizabeth et al. (2017) Using Stakeholder Input to Inform an Innovative Research and Policy Initiative to Improve Depression in Safety Net Communities. Prog Community Health Partnersh 11:93-98
Ong, Michael K; Jones, Loretta; Aoki, Wayne et al. (2017) A Community-Partnered, Participatory, Cluster-Randomized Study of Depression Care Quality Improvement: Three-Year Outcomes. Psychiatr Serv 68:1262-1270
Miranda, Jeanne; Bromley, Elizabeth; Izquierdo, Adriana et al. (2017) Surviving Depression: Clinical Qualitative Analysis of Long-Term Survival for Ethnically Diverse, Depressed Patients. J Nerv Ment Dis 205:589-599
Paz, Sylvia H; Jones, Loretta; Calderón, José L et al. (2017) Readability and Comprehension of the Geriatric Depression Scale and PROMIS® Physical Function Items in Older African Americans and Latinos. Patient 10:117-131
Sherbourne, Cathy D; Aoki, Wayne; Belin, Thomas R et al. (2017) Comparative Effectiveness of Two Models of Depression Services Quality Improvement in Health and Community Sectors. Psychiatr Serv 68:1315-1320
Landry, Craig M; Jackson, Aurora P; Tang, Lingqi et al. (2017) The Effects of Collaborative Care Training on Case Managers' Perceived Depression-Related Services Delivery. Psychiatr Serv 68:123-130
Ngo, Victoria K; Sherbourne, Cathy; Chung, Bowen et al. (2016) Community Engagement Compared With Technical Assistance to Disseminate Depression Care Among Low-Income, Minority Women: A Randomized Controlled Effectiveness Study. Am J Public Health 106:1833-41
Lam, Christine A; Sherbourne, Cathy; Tang, Lingqi et al. (2016) The Impact of Community Engagement on Health, Social, and Utilization Outcomes in Depressed, Impoverished Populations: Secondary Findings from a Randomized Trial. J Am Board Fam Med 29:325-38