Our long term goal is to reduce oral health disparities in rural school children. Our immediate goal is to test two new evidence-based, school-based, cavity prevention programs. We will compare two preventions: (1) A newer, simpler, less expensive, efficient treatment using fluoride varnish + silver diamine fluoride; and (2) A more traditional, complex, expensive, time-intensive treatment that includes simple + sealants + interim therapeutic restorations. The simpler method takes 6 minutes to deliver, compared to the more complex method that takes 20 minutes. Therefore, if the simpler, less expensive is as effective as the more complex, more expensive method, the data could support clinical and policy change. To compare the two methods we will use a cluster randomized control trial design. We will implement this program in rural New Hampshire schools. All children in a school with informed consent will receive the same treatment (either simple or complex). We will provide preventive care twice per year for the 5 year grant period. We will follow all children longitudinally for five years to determine the effectiveness of each preventive method. The primary outcome to make this determination will be the percentage of children with untreated decay. This is one of the U.S. Healthy People oral health goals. We will also examine the cost and cost- effectiveness. This will allow us to determine the balance between effectiveness and cost. Assessing effectiveness and costs is particularly important for reducing disparities. If an intervention is quick, inexpensive, and 100% effective, that is a relatively simple choice. Most interventions are not 100% effective. Therefore, information on time, expense, and effectiveness will allow us to make better informed clinical and policy decisions. Specifically, this will help us answer the question: How much of which preventive intervention will increase access, improve health, and reduce costs?

Public Health Relevance

Dental cavities are world?s most prevalent disease. In the U.S., almost 4 in 10 rural schoolchildren have untreated cavities. To improve the health of children we will test two new school- based cavity prevention programs to see which works best.

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Research Project (R01)
Project #
5R01MD011526-03
Application #
9691490
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Alvidrez, Jennifer L
Project Start
2017-09-20
Project End
2022-04-30
Budget Start
2019-05-01
Budget End
2020-04-30
Support Year
3
Fiscal Year
2019
Total Cost
Indirect Cost
Name
New York University
Department
Public Health & Prev Medicine
Type
Schools of Dentistry/Oral Hygn
DUNS #
041968306
City
New York
State
NY
Country
United States
Zip Code
10012
Ruff, Ryan Richard; Niederman, Richard (2018) Comparative effectiveness of treatments to prevent dental caries given to rural children in school-based settings: protocol for a cluster randomised controlled trial. BMJ Open 8:e022646
Oliveira, Branca Heloisa; Cunha-Cruz, Joana; Rajendra, Anjana et al. (2018) Controlling caries in exposed root surfaces with silver diamine fluoride: A systematic review with meta-analysis. J Am Dent Assoc 149:671-679.e1
Oliveira, Branca Heloisa; Rajendra, Anjana; Veitz-Keenan, Analia et al. (2018) The Effect of Silver Diamine Fluoride in Preventing Caries in the Primary Dentition: A Systematic Review and Meta-Analysis. Caries Res 53:24-32