The proposed study represents the follow-up evaluation phase of the """"""""Clinical Validity of the DSM-III Diagnostic System"""""""" study in progress at Western Psychiatric Institute and Clinic. The objective of the proposed research is to investigate empirically the predictive validity of major components of the DSM-III multiaxial diagnostic system. This type of validity represents an evaluative criterion encompassing the strongest combination of scientific value and clinical usefulness. Predictive validity studies will focus on the ability of the initial diagnostic judgments to predict treatment utilization patterns (both inpatient and outpatient), as well as outcome variables such as symptomatological status and adaptive functioning. Additionally, some aspects of the course and stability of illness will be considered. The proposed study will involve the follow-up evaluation of the approximately 500 participants in the baseline study in progress at WPIC. Thirty-three months after the baseline evaluation, participants will be scheduled for a follow-up assessment. This will consist of a diagnostic interview covering the five axes of DSM-III (I. Psychiatric Syndromes, II. Personality Disorders, III. Physical Disorders, IV. Psychosocial Stressors, V. Highest Level of Adaptive Functioning in the Past Year) and an additional sixth axis routinely used at WPIC (VI. Current Functioning at Work/School, with Family and with other Individuals and Groups). In addition, instruments to appraise various aspects of treatment utilization, patient outcome, and course of illness will be employed. The evaluating team conducting each follow-up assessment will consist of a master's level clinician experienced in psychiatric assessment working in collaboration with a faculty clinical psychiatrist. The approximate length of the interview will be 2-1/2 hours. The research questions posed in the proposal will be answered through frequency analyses and discrete multivariate analyses addressing the value of major diagnostic categories in Axis I for the prediction of treatment utilization patterns and outcome at the thirty-three month follow-up assessment. Furthermore, enhancement of the predictive validity of Axis I by the other Axes in DSM-III will also be examined.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH037116-06
Application #
3376047
Study Section
(EPSA)
Project Start
1984-01-01
Project End
1990-12-31
Budget Start
1989-01-01
Budget End
1990-12-31
Support Year
6
Fiscal Year
1989
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Salloum, I M; Mezzich, J E; Cornelius, J et al. (1995) Clinical profile of comorbid major depression and alcohol use disorders in an initial psychiatric evaluation. Compr Psychiatry 36:260-6
Mezzich, J E (1989) International diagnostic systems and Latin-American contributions and issues. Br J Psychiatry Suppl :84-90
Mezzich, J E; Fabrega Jr, H; Coffman, G A et al. (1989) DSM-III disorders in a large sample of psychiatric patients: frequency and specificity of diagnoses. Am J Psychiatry 146:212-9
Mezzich, J E; Fabrega Jr, H; Coffman, G A (1987) Multiaxial characterization of depressive patients. J Nerv Ment Dis 175:339-46
Mezzich, J E; Fabrega Jr, H; Coffman, G A et al. (1987) Comprehensively diagnosing geriatric patients. Compr Psychiatry 28:68-76
Mezzich, J E; Coffman, G A (1985) Factors influencing length of hospital stay. Hosp Community Psychiatry 36:1262-4, 1270