This proposed study represents an extension of the Yale Epidemiologic Catchment Area (ECA) Project with the transition in funding from a cooperative agreement to a RO1 grant. The ECA is a large scale multisite epidemiologic community survey of psychiatric disorders in five US communities: New Haven, Eastern Baltimore, St. Louis, Piedmont, and Los Angeles. Information on the rates, correlates, and course of psychiatric disorders and treatment utilization on over 15,000 persons living in the community and in institutions has been collected. Considerable progress has been made in the methodology for collecting and managing data and in conducting basic analysis of the data available. Because of the sequence in which the ECA sites were funded, cross-sectional and longitudinal data from all five ECA sites and all waves will be available to us for the first time for analysis by January, 1986 when our current funding ends. We are now requesting two years of funding in order to extend our epidemiologic analysis of data to include data from all five sites and all waves. This proposal focuses on analyses in two areas where the investigators have considerable expertise and active research programs.
Our aim i s to use both the cross-sectional and the longitudinal epidemiologic data from all five sites to: (1) understand the epidemiology of the affective disorders, their subtypes, their subclinical manifestations and their overlap with other disorders particularly anxiety disorders, and (2) conduct analyses of mental health related treatment taking into account subclinical cases and determining the extent to which there is differential utilization by specific subpopulations.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH040603-02
Application #
3378875
Study Section
(EPSA)
Project Start
1986-03-01
Project End
1989-03-31
Budget Start
1987-03-01
Budget End
1989-03-31
Support Year
2
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Yale University
Department
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Weissman, M M; Greenwald, S; Nino-Murcia, G et al. (1997) The morbidity of insomnia uncomplicated by psychiatric disorders. Gen Hosp Psychiatry 19:245-50
Horwitz, S M; Bruce, M L; Hoff, R A et al. (1996) Depression in former school-age mothers and community comparison subjects. J Affect Disord 40:95-103
Bruce, M L; Hoff, R A; Jacobs, S C et al. (1995) The effects of cognitive impairment on 9-year mortality in a community sample. J Gerontol B Psychol Sci Soc Sci 50:P289-96
Bruce, M L; Hoff, R A (1994) Social and physical health risk factors for first-onset major depressive disorder in a community sample. Soc Psychiatry Psychiatr Epidemiol 29:165-71
Bruce, M L; Leaf, P J; Rozal, G P et al. (1994) Psychiatric status and 9-year mortality data in the New Haven Epidemiologic Catchment Area Study. Am J Psychiatry 151:716-21
Bruce, M L; McNamara, R (1992) Psychiatric status among the homebound elderly: an epidemiologic perspective. J Am Geriatr Soc 40:561-6
Krystal, J H; Leaf, P J; Bruce, M L et al. (1992) Effects of age and alcoholism on the prevalence of panic disorder. Acta Psychiatr Scand 85:77-82
Bruce, M L; Kim, K M (1992) Differences in the effects of divorce on major depression in men and women. Am J Psychiatry 149:914-7
Bruce, M L; Takeuchi, D T; Leaf, P J (1991) Poverty and psychiatric status. Longitudinal evidence from the New Haven Epidemiologic Catchment Area study. Arch Gen Psychiatry 48:470-4
Bruce, M L; Kim, K; Leaf, P J et al. (1990) Depressive episodes and dysphoria resulting from conjugal bereavement in a prospective community sample. Am J Psychiatry 147:608-11

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