The purpose of this study is to investigate and clarify the relationship between physical illness and depression among the elderly. Although there exists strong support for the conclusion that depressive disorders are closely related to physical illness, none of the existing studies answer important questions about the mediating mechanisms which may account for this relationship. Two general types of explanations have been suggested to explain the co-ocurrence of depression and physical illness: the biological factors explanation argues that symptoms of depression are a direct consequence of illness or a side effect of medication; the psychosocial stress factors explanation emphasizes the occurrence and personal significance of the stress associated with being physically ill. To test the relative importance of these factors, a prospective study is proposed in which 300 geriatric outpatients will be assessed at six month intervals over a period of eighteen months. All patients will undergo detailed medical evaluations and complete a psychosocial survey designed to assess individual and disease characteristics that may play a role in the relationship between physical illness and depression. Multivariate analytic techniques and structural modeling procedures will be used to analyze the longitudinal data and to test causal models linking physical illness with depression.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH041887-02
Application #
3380815
Study Section
(LCRB)
Project Start
1986-07-01
Project End
1989-06-30
Budget Start
1987-07-01
Budget End
1988-06-30
Support Year
2
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Heckhausen, J; Schulz, R (1995) A life-span theory of control. Psychol Rev 102:284-304
Williamson, G M; Schulz, R (1995) Activity restriction mediates the association between pain and depressed affect: a study of younger and older adult cancer patients. Psychol Aging 10:369-78
Schulz, R; Williamson, G M (1993) Psychosocial and behavioral dimensions of physical frailty. J Gerontol 48 Spec No:39-43
Williamson, G M; Schulz, R (1992) Physical illness and symptoms of depression among elderly outpatients. Psychol Aging 7:343-51
Williamson, G M; Schulz, R (1992) Pain, activity restriction, and symptoms of depression among community-residing elderly adults. J Gerontol 47:P367-72
Schulz, R; Visintainer, P; Williamson, G M (1990) Psychiatric and physical morbidity effects of caregiving. J Gerontol 45:P181-91
Fischer, L; Visintainer, P F; Schulz, R (1989) Reliable assessment of cognitive impairment in dementia patients by family caregivers. Gerontologist 29:333-5