Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH042217-08
Application #
2245402
Study Section
Neurosciences Research Review Committee (BPN)
Project Start
1991-09-30
Project End
1997-08-31
Budget Start
1995-09-01
Budget End
1997-08-31
Support Year
8
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Onn, S P; Grace, A A (1999) Alterations in electrophysiological activity and dye coupling of striatal spiny and aspiny neurons in dopamine-denervated rat striatum recorded in vivo. Synapse 33:1-15
Todd, C L; Grace, A A (1999) Interaction of benztropine and haloperidol actions on rat substantia nigra dopamine cell electrophysiological activity in vivo. Brain Res Bull 48:219-22
O'Donnell, P; Grace, A A (1998) Dysfunctions in multiple interrelated systems as the neurobiological bases of schizophrenic symptom clusters. Schizophr Bull 24:267-83
Lavin, A; Grace, A A (1996) Physiological properties of rat ventral pallidal neurons recorded intracellularly in vivo. J Neurophysiol 75:1432-43
Pucak, M L; Grace, A A (1996) Effects of haloperidol on the activity and membrane physiology of substantia nigra dopamine neurons recorded in vitro. Brain Res 713:44-52
O'Donnell, P; Grace, A A (1996) Dopaminergic reduction of excitability in nucleus accumbens neurons recorded in vitro. Neuropsychopharmacology 15:87-97
Grace, A A (1995) The tonic/phasic model of dopamine system regulation: its relevance for understanding how stimulant abuse can alter basal ganglia function. Drug Alcohol Depend 37:111-29
Harden, D G; Grace, A A (1995) Activation of dopamine cell firing by repeated L-DOPA administration to dopamine-depleted rats: its potential role in mediating the therapeutic response to L-DOPA treatment. J Neurosci 15:6157-66
O'Donnell, P; Grace, A A (1995) Different effects of subchronic clozapine and haloperidol on dye-coupling between neurons in the rat striatal complex. Neuroscience 66:763-7
O'Donnell, P; Grace, A A (1995) Synaptic interactions among excitatory afferents to nucleus accumbens neurons: hippocampal gating of prefrontal cortical input. J Neurosci 15:3622-39

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