Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
7R01MH042572-01
Application #
3381763
Study Section
(BPNB)
Project Start
1986-07-01
Project End
1987-06-30
Budget Start
1986-07-01
Budget End
1987-06-30
Support Year
1
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Loyola University Chicago
Department
Type
Schools of Dentistry/Oral Hygn
DUNS #
791277940
City
Maywood
State
IL
Country
United States
Zip Code
60153
Santiago, L R; Erickson, L C; Hanin, I (1998) AF64A-induced changes in N-myc expression in the LA-N-2 human neuroblastoma cell line are modulated by choline and hemicholinium-3. Neurochem Res 23:743-50
Santiago, L R; Ivy, M T; Erickson, L C et al. (1995) AF64A-induced cytotoxicity and changes in choline acetyltransferase activity in the LA-N-2 neuroblastoma cell line are modulated by choline and hemicholinium-3. J Neurosci Methods 61:185-90
Dong, X W; Hanin, I; Lorens, S A (1994) AF64A affects septal choline acetyltransferase but not parvalbumin immunoreactive cells. Brain Res Bull 35:217-20
Hortnagl, H; Hansen, L; Kindel, G et al. (1993) Sex differences and estrous cycle-variations in the AF64A-induced cholinergic deficit in the rat hippocampus. Brain Res Bull 31:129-34
Mistry, J S; Abraham, D J; Kozikowski, A P et al. (1991) Neurochemistry of aging. 2. Design, synthesis, and biological evaluation of halomethyl analogues of choline with high affinity choline transport inhibitory activity. J Med Chem 34:2031-6
Chrobak, J J; Napier, T C; Hanin, I et al. (1991) The pharmacology of basal forebrain involvement in cognition. Adv Exp Med Biol 295:383-98
Laganiere, S; Corey, J; Tang, X C et al. (1991) Acute and chronic studies with the anticholinesterase Huperzine A: effect on central nervous system cholinergic parameters. Neuropharmacology 30:763-8
Lorens, S A; Kindel, G; Dong, X W et al. (1991) Septal choline acetyltransferase immunoreactive neurons: dose-dependent effects of AF64A. Brain Res Bull 26:965-71
Laganiere, S; Marinko, M; Corey, J et al. (1990) Sector-dependent neurotoxicity of ethylcholine aziridinium (AF64A) in the rat hippocampus. Neuropharmacology 29:961-4
Hanin, I (1990) AF64A-induced cholinergic hypofunction. Prog Brain Res 84:289-99

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