Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH042796-08
Application #
2245538
Study Section
Neuropharmacology and Neurochemistry Review Committee (NPNC)
Project Start
1989-07-01
Project End
1997-12-31
Budget Start
1996-02-15
Budget End
1996-12-31
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Allegheny University of Health Sciences
Department
Psychiatry
Type
Schools of Medicine
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19129
Curtis, A L; Pavcovich, L A; Valentino, R J (1999) Long-term regulation of locus ceruleus sensitivity to corticotropin-releasing factor by swim stress. J Pharmacol Exp Ther 289:1211-9
Lechner, S M; Valentino, R J (1999) Glucocorticoid receptor-immunoreactivity in corticotrophin-releasing factor afferents to the locus coeruleus. Brain Res 816:17-28
Pavcovich, L A; Valentino, R J (1997) Regulation of a putative neurotransmitter effect of corticotropin-releasing factor: effects of adrenalectomy. J Neurosci 17:401-8
Lechner, S M; Curtis, A L; Brons, R et al. (1997) Locus coeruleus activation by colon distention: role of corticotropin-releasing factor and excitatory amino acids. Brain Res 756:114-24
Valentino, R J; Chen, S; Zhu, Y et al. (1996) Evidence for divergent projections to the brain noradrenergic system and the spinal parasympathetic system from Barrington's nucleus. Brain Res 732:1-15
Curtis, A L; Pavcovich, L A; Grigoriadis, D E et al. (1995) Previous stress alters corticotropin-releasing factor neurotransmission in the locus coeruleus. Neuroscience 65:541-50
Pavcovich, L A; Valentino, R J (1995) Central regulation of micturition in the rat the corticotropin-releasing hormone from Barrington's nucleus. Neurosci Lett 196:185-8
Curtis, A L; Grigoriadis, D E; Page, M E et al. (1994) Pharmacological comparison of two corticotropin-releasing factor antagonists: in vivo and in vitro studies. J Pharmacol Exp Ther 268:359-65
Valentino, R J; Foote, S L; Page, M E (1993) The locus coeruleus as a site for integrating corticotropin-releasing factor and noradrenergic mediation of stress responses. Ann N Y Acad Sci 697:173-88
Curtis, A L; Drolet, G; Valentino, R J (1993) Hemodynamic stress activates locus coeruleus neurons of unanesthetized rats. Brain Res Bull 31:737-44

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