Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
7R01MH042859-05
Application #
2245580
Study Section
Psychopathology and Clinical Biology Research Review Committee (PCB)
Project Start
1989-05-01
Project End
1995-08-31
Budget Start
1994-05-01
Budget End
1995-08-31
Support Year
5
Fiscal Year
1992
Total Cost
Indirect Cost
Name
University of Mississippi Medical Center
Department
Psychiatry
Type
Schools of Medicine
DUNS #
928824473
City
Jackson
State
MS
Country
United States
Zip Code
39216
Piletz, John; Baker, Robert; Halaris, Angelos (2008) Platelet imidazoline receptors as state marker of depressive symptomatology. J Psychiatr Res 42:41-9
Piletz, J E; Ordway, G A; Zhu, H et al. (2000) Autoradiographic comparison of [3H]-clonidine binding to non-adrenergic sites and alpha(2)-adrenergic receptors in human brain. Neuropsychopharmacology 23:697-708
Zhu, H; Halaris, A; Madakasira, S et al. (1999) Effect of bupropion on immunodensity of putative imidazoline receptors on platelets of depressed patients. J Psychiatr Res 33:323-33
Halaris, A; Zhu, H; Feng, Y et al. (1999) Plasma agmatine and platelet imidazoline receptors in depression. Ann N Y Acad Sci 881:445-51
Piletz, J E; Andrew, M; Zhu, H et al. (1998) Alpha 2-adrenoceptors and I1-imidazoline binding sites: relationship with catecholamines in women of reproductive age. J Psychiatr Res 32:55-64
Zhu, H; Halaris, A; Piletz, J E (1997) Chronic imipramine treatment downregulates IR1-imidazoline receptors in rat brainstem. Life Sci 61:1973-83
Piletz, J E; Halaris, A; Nelson, J et al. (1996) Platelet I1-imidazoline binding sites are elevated in depression but not generalized anxiety disorder. J Psychiatr Res 30:147-68
Piletz, J E; Halaris, A E; Chikkala, D et al. (1996) Platelet I1-imidazoline binding sites are decreased by two dissimilar antidepressant agents in depressed patients. J Psychiatr Res 30:169-84
Piletz, J E; Zhu, H; Chikkala, D N (1996) Comparison of ligand binding affinities at human I1-imidazoline binding sites and the high affinity state of alpha-2 adrenoceptor subtypes. J Pharmacol Exp Ther 279:694-702
Piletz, J E; Halaris, A; Ernsberger, P R (1994) Psychopharmacology of imidazoline and alpha 2-adrenergic receptors: implications for depression. Crit Rev Neurobiol 9:29-66

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