Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH045481-07
Application #
2033772
Study Section
Neuropharmacology and Neurochemistry Review Committee (NPNC)
Project Start
1989-09-01
Project End
2000-04-30
Budget Start
1996-09-15
Budget End
1997-04-30
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Kato, T; Fogaça, M V; Deyama, S et al. (2018) BDNF release and signaling are required for the antidepressant actions of GLYX-13. Mol Psychiatry 23:2007-2017
Ghosal, Sriparna; Bang, Eunyoung; Yue, Wenzhu et al. (2018) Activity-Dependent Brain-Derived Neurotrophic Factor Release Is Required for the Rapid Antidepressant Actions of Scopolamine. Biol Psychiatry 83:29-37
Hare, Brendan D; Ghosal, Sriparna; Duman, Ronald S (2017) Rapid Acting Antidepressants in Chronic Stress Models: Molecular and Cellular Mechanisms. Chronic Stress (Thousand Oaks) 1:
Wohleb, Eric S; Wu, Min; Gerhard, Danielle M et al. (2016) GABA interneurons mediate the rapid antidepressant-like effects of scopolamine. J Clin Invest 126:2482-94
Duman, Ronald S; Aghajanian, George K; Sanacora, Gerard et al. (2016) Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants. Nat Med 22:238-49
Duman, Ronald S; Aghajanian, George K (2014) Neurobiology of rapid acting antidepressants: role of BDNF and GSK-3?. Neuropsychopharmacology 39:233
Voleti, Bhavya; Navarria, Andrea; Liu, Rong-Jian et al. (2013) Scopolamine rapidly increases mammalian target of rapamycin complex 1 signaling, synaptogenesis, and antidepressant behavioral responses. Biol Psychiatry 74:742-9
Duric, Vanja; Banasr, Mounira; Stockmeier, Craig A et al. (2013) Altered expression of synapse and glutamate related genes in post-mortem hippocampus of depressed subjects. Int J Neuropsychopharmacol 16:69-82
Iwata, Masaaki; Ota, Kristie T; Duman, Ronald S (2013) The inflammasome: pathways linking psychological stress, depression, and systemic illnesses. Brain Behav Immun 31:105-14
Ota, Kristie T; Duman, Ronald S (2013) Environmental and pharmacological modulations of cellular plasticity: role in the pathophysiology and treatment of depression. Neurobiol Dis 57:28-37

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