This proposal is for a competitive renewal of a study that compares the cost-effectiveness of two approaches to treating people who have dual diagnoses of severe mental illness and substance use disorders. We contrast Continuous Treatment Teams (CTT), which integrate direct treatment for substance abuse and psychiatric disorders in an intensive outreach approach, with traditional Community Support Programs (CSP), in which case managers seek to link clients to appropriate treatment providers. We are requesting funding to complete the study as originally proposed and to extend the follow-up period from two to three years. Two hundred forty clients have been randomly assigned to either CTT or CSP at a total of seven Community Mental Health Centers (CMHCs) in New Hampshire. Implementation of the two treatment models has been monitored carefully, and our initial data show that CTT and CSP approaches differ significantly in the types and amounts of treatment. Since our original submission, we have tested and refined our procedures for measuring the social (societal) costs associated with dual diagnoses. In response to the review committee's request, we have also developed an approach for combining multiple outcomes in a cost-utility analysis (CA). The CA considers the utility of treatment from the perspectives of three groups: clients, families, and treatment providers. Because of difficulties associated with dual disorders, these clients are widely believed to be particularly high resource users. We hypothesize that total resource use by CTT clients will decrease over time, even though the initial investment of time and resources per patient may be greater than that of the CSP approach, and that CTT will be more cost-effective than CSP within the three year follow-up period. Questions of social costs such as community and family burden have become more important as people with severe mental illness spend less time in hospitals and more time at home or in the community. Previous mental health cost studies used indirect methods for estimating community and family costs, measured them incompletely, or used crude estimates. In this study we have improved on existing techniques for documenting use and costs of community and family resources. We hypothesize that CTT clients will use fewer family and community resources than CSP clients during the follow-up period.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
2R01MH047567-03
Application #
2247720
Study Section
Epidemiologic and Services Research Review Committee (EPS)
Project Start
1990-09-30
Project End
1994-12-31
Budget Start
1992-09-01
Budget End
1993-08-31
Support Year
3
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Dartmouth College
Department
Psychiatry
Type
Schools of Medicine
DUNS #
041027822
City
Hanover
State
NH
Country
United States
Zip Code
03755
Xie, Haiyi; McHugo, Gregory; Sengupta, Anjana et al. (2004) A method for analyzing longitudinal outcomes with many zeros. Ment Health Serv Res 6:239-46
Xie, Haiyi; McHugo, Gregory; Drake, Robert et al. (2003) Using discrete-time survival analysis to examine patterns of remission from substance use disorder among persons with severe mental illness. Ment Health Serv Res 5:55-64
Nixon, John; Phipps, Kate; Glanville, Julie et al. (2002) Using economic evidence to support decision making: a case study of assertive community treatment within the UK National Service Framework for Mental Health. Appl Health Econ Health Policy 1:179-90
Alverson, H; Alverson, M; Drake, R E (2001) Social patterns of substance use among people with dual diagnoses. Ment Health Serv Res 3:3-14
Clark, R E (2001) Family support and substance use outcomes for persons with mental illness and substance use disorders. Schizophr Bull 27:93-101
Drake, R E; Xie, H; McHugo, G J et al. (2000) The effects of clozapine on alcohol and drug use disorders among patients with schizophrenia. Schizophr Bull 26:441-9
Alverson, H; Alverson, M; Drake, R E (2000) An ethnographic study of the longitudinal course of substance abuse among people with severe mental illness. Community Ment Health J 36:557-69
McHugo, G J; Drake, R E; Teague, G B et al. (1999) Fidelity to assertive community treatment and client outcomes in the New Hampshire dual disorders study. Psychiatr Serv 50:818-24
Clark, R E; Ricketts, S K; McHugo, G J (1999) Legal system involvement and costs for persons in treatment for severe mental illness and substance use disorders. Psychiatr Serv 50:641-7
Teague, G B; Bond, G R; Drake, R E (1998) Program fidelity in assertive community treatment: development and use of a measure. Am J Orthopsychiatry 68:216-32

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