Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
2R01MH049165-04A1
Application #
2248697
Study Section
Diagnostic Radiology Study Section (RNM)
Project Start
1992-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Associated University-Brookhaven National Lab
Department
Type
DUNS #
City
Upton
State
NY
Country
United States
Zip Code
11973
Marsteller, Douglas A; Gerasimov, Madina R; Schiffer, Wynne K et al. (2002) Acute handling stress modulates methylphenidate-induced catecholamine overflow in the medial prefrontal cortex. Neuropsychopharmacology 27:163-70
Gerasimov, M R; Schiffer, W K; Gardner, E L et al. (2001) GABAergic blockade of cocaine-associated cue-induced increases in nucleus accumbens dopamine. Eur J Pharmacol 414:205-9
Schiffer, W K; Gerasimov, M R; Marsteller, D A et al. (2001) Topiramate selectively attenuates nicotine-induced increases in monoamine release. Synapse 42:196-8
Schiffer, W K; Gerasimov, M; Hofmann, L et al. (2001) Gamma vinyl-GABA differentially modulates NMDA antagonist-induced increases in mesocortical versus mesolimbic DA transmission. Neuropsychopharmacology 25:704-12
Gerasimov, M R; Schiffer, W K; Brodie, J D et al. (2000) gamma-aminobutyric acid mimetic drugs differentially inhibit the dopaminergic response to cocaine. Eur J Pharmacol 395:129-35
Gerasimov, M R; Franceschi, M; Volkow, N D et al. (2000) Comparison between intraperitoneal and oral methylphenidate administration: A microdialysis and locomotor activity study. J Pharmacol Exp Ther 295:51-7
Gerasimov, M R; Franceschi, M; Volkow, N D et al. (2000) Synergistic interactions between nicotine and cocaine or methylphenidate depend on the dose of dopamine transporter inhibitor. Synapse 38:432-7
Schiffer, W K; Gerasimov, M R; Bermel, R A et al. (2000) Stereoselective inhibition of dopaminergic activity by gamma vinyl-GABA following a nicotine or cocaine challenge: a PET/microdialysis study. Life Sci 66:PL169-73
Dewey, S L; Brodie, J D; Gerasimov, M et al. (1999) A pharmacologic strategy for the treatment of nicotine addiction. Synapse 31:76-86
Gerasimov, M R; Dewey, S L (1999) Gamma-vinyl gamma-aminobutyric acid attenuates the synergistic elevations of nucleus accumbens dopamine produced by a cocaine/heroin (speedball) challenge. Eur J Pharmacol 380:1-4

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