Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
1R01MH052685-01A2
Application #
2252536
Study Section
Psychobiology, Behavior, and Neuroscience Review Committee (PBN)
Project Start
1996-05-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Northwestern University at Chicago
Department
Pharmacology
Type
Schools of Dentistry
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Liu, Jiabei; Clough, Shannon J; Hutchinson, Anthony J et al. (2016) MT1 and MT2 Melatonin Receptors: A Therapeutic Perspective. Annu Rev Pharmacol Toxicol 56:361-83
Jockers, Ralf; Delagrange, Philippe; Dubocovich, Margarita L et al. (2016) Update on melatonin receptors: IUPHAR Review 20. Br J Pharmacol 173:2702-25
Dubocovich, Margarita L; Delagrange, Philippe; Krause, Diana N et al. (2010) International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, classification, and pharmacology of G protein-coupled melatonin receptors. Pharmacol Rev 62:343-80
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Dubocovich, Margarita L (2007) Melatonin receptors: role on sleep and circadian rhythm regulation. Sleep Med 8 Suppl 3:34-42
Dubocovich, Margarita L; Markowska, Magdalena (2005) Functional MT1 and MT2 melatonin receptors in mammals. Endocrine 27:101-10
Blask, David E; Brainard, George C; Dauchy, Robert T et al. (2005) Melatonin-depleted blood from premenopausal women exposed to light at night stimulates growth of human breast cancer xenografts in nude rats. Cancer Res 65:11174-84
Dubocovich, M L; Hudson, R L; Sumaya, I C et al. (2005) Effect of MT1 melatonin receptor deletion on melatonin-mediated phase shift of circadian rhythms in the C57BL/6 mouse. J Pineal Res 39:113-20
Sumaya, I C; Masana, M I; Dubocovich, M L (2005) The antidepressant-like effect of the melatonin receptor ligand luzindole in mice during forced swimming requires expression of MT2 but not MT1 melatonin receptors. J Pineal Res 39:170-7
Gerdin, Matthew J; Masana, Monica I; Rivera-Bermudez, Moises A et al. (2004) Melatonin desensitizes endogenous MT2 melatonin receptors in the rat suprachiasmatic nucleus: relevance for defining the periods of sensitivity of the mammalian circadian clock to melatonin. FASEB J 18:1646-56

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