Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
1R01MH053814-01A2
Application #
2254064
Study Section
AIDS and Related Research Study Section 7 (ARRG)
Project Start
1996-08-01
Project End
1999-04-30
Budget Start
1996-08-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Stanford University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Munhoz, Carolina Demarchi; Sorrells, Shawn F; Caso, Javier R et al. (2010) Glucocorticoids exacerbate lipopolysaccharide-induced signaling in the frontal cortex and hippocampus in a dose-dependent manner. J Neurosci 30:13690-8
Zemlyak, Ilona; Brooke, Sheila; Sapolsky, Robert (2005) Estrogenic protection against gp120 neurotoxicity: role of microglia. Brain Res 1046:130-6
Dinkel, Klaus; Dhabhar, Firdaus S; Sapolsky, Robert M (2004) Neurotoxic effects of polymorphonuclear granulocytes on hippocampal primary cultures. Proc Natl Acad Sci U S A 101:331-6
Brooke, Sheila M; Sapolsky, Robert M (2003) Effects of glucocorticoids in the gp120-induced inhibition of glutamate uptake in hippocampal cultures. Brain Res 972:137-41
Lim, Min Chin; Brooke, Sheila M; Sapolsky, Robert M (2003) gp120 neurotoxicity fails to induce heat shock defenses, while the over expression of hsp70 protects against gp120. Brain Res Bull 61:183-8
Dinkel, Klaus; MacPherson, Anna; Sapolsky, Robert M (2003) Novel glucocorticoid effects on acute inflammation in the CNS. J Neurochem 84:705-16
Zemlyak, Ilona; Brooke, Sheila M; Sapolsky, Robert M (2002) Protection against gp120-induced neurotoxicity by an array of estrogenic steroids. Brain Res 958:272-6
Brooke, Sheila M; Sapolsky, Robert M (2002) Glucocorticoid exacerbation of gp120 neurotoxicity: role of microglia. Exp Neurol 177:151-8
Patel, Ravi; McIntosh, Laura; McLaughlin, John et al. (2002) Disruptive effects of glucocorticoids on glutathione peroxidase biochemistry in hippocampal cultures. J Neurochem 82:118-25
Dinkel, Klaus; Ogle, William O; Sapolsky, Robert M (2002) Glucocorticoids and central nervous system inflammation. J Neurovirol 8:513-28

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