Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH054718-08
Application #
6779098
Study Section
Special Emphasis Panel (ZRG1-BDCN-4 (01))
Program Officer
Winsky, Lois M
Project Start
1996-04-01
Project End
2006-06-30
Budget Start
2004-07-20
Budget End
2005-06-30
Support Year
8
Fiscal Year
2004
Total Cost
$217,500
Indirect Cost
Name
University of Connecticut
Department
Pharmacology
Type
Schools of Medicine
DUNS #
022254226
City
Farmington
State
CT
Country
United States
Zip Code
06030
Murugesan, Nivetha; Demarest, Tyler G; Madri, Joseph A et al. (2012) Brain regional angiogenic potential at the neurovascular unit during normal aging. Neurobiol Aging 33:1004.e1-16
Murugesan, Nivetha; Macdonald, Jennifer A; Lu, Qiaozhan et al. (2011) Analysis of mouse brain microvascular endothelium using laser capture microdissection coupled with proteomics. Methods Mol Biol 686:297-311
Murugesan, Nivetha; Macdonald, Jennifer; Ge, Shujun et al. (2011) Probing the CNS microvascular endothelium by immune-guided laser-capture microdissection coupled to quantitative RT-PCR. Methods Mol Biol 755:385-94
Macdonald, Jennifer A; Murugesan, Nivetha; Pachter, Joel S (2010) Endothelial cell heterogeneity of blood-brain barrier gene expression along the cerebral microvasculature. J Neurosci Res 88:1457-74
Macdonald, Jennifer A; Murugesan, Nivetha; Pachter, Joel S (2008) Validation of immuno-laser capture microdissection coupled with quantitative RT-PCR to probe blood-brain barrier gene expression in situ. J Neurosci Methods 174:219-26
Lu, Qiaozhen; Murugesan, Nivetha; Macdonald, Jennifer A et al. (2008) Analysis of mouse brain microvascular endothelium using immuno-laser capture microdissection coupled to a hybrid linear ion trap with Fourier transform-mass spectrometry proteomics platform. Electrophoresis 29:2689-95
Song, Li; Ge, Shujun; Pachter, Joel S (2007) Caveolin-1 regulates expression of junction-associated proteins in brain microvascular endothelial cells. Blood 109:1515-23
Ge, Shujun; Pachter, Joel S (2006) Isolation and culture of microvascular endothelial cells from murine spinal cord. J Neuroimmunol 177:209-14
Kinnecom, Katie; Pachter, Joel S (2005) Selective capture of endothelial and perivascular cells from brain microvessels using laser capture microdissection. Brain Res Brain Res Protoc 16:1-9
Dzenko, Kirk A; Song, Li; Ge, Shujun et al. (2005) CCR2 expression by brain microvascular endothelial cells is critical for macrophage transendothelial migration in response to CCL2. Microvasc Res 70:53-64

Showing the most recent 10 out of 18 publications