Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH056220-02
Application #
2728156
Study Section
Project Start
1997-05-01
Project End
2000-04-30
Budget Start
1998-05-01
Budget End
1999-04-30
Support Year
2
Fiscal Year
1998
Total Cost
Indirect Cost
Azab, Abed N; He, Quan; Ju, Shulin et al. (2007) Glycogen synthase kinase-3 is required for optimal de novo synthesis of inositol. Mol Microbiol 63:1248-58
Azab, Abed N; Greenberg, Miriam L (2007) Anticonvulsant efficacy of valproate-like carboxylic acids: a potential target for anti-bipolar therapy. Bipolar Disord 9:197-205
Shi, Yihui; Azab, Abed N; Thompson, Morgan N et al. (2006) Inositol phosphates and phosphoinositides in health and disease. Subcell Biochem 39:265-92
Shi, Yihui; Vaden, Deirdre L; Ju, Shulin et al. (2005) Genetic perturbation of glycolysis results in inhibition of de novo inositol biosynthesis. J Biol Chem 280:41805-10
Vaden, Deirdre L; Gohil, Vishal M; Gu, Zhiming et al. (2005) Separation of yeast phospholipids using one-dimensional thin-layer chromatography. Anal Biochem 338:162-4
Ju, Shulin; Shaltiel, Galit; Shamir, Alon et al. (2004) Human 1-D-myo-inositol-3-phosphate synthase is functional in yeast. J Biol Chem 279:21759-65
Shaltiel, Galit; Shamir, Alon; Shapiro, Joseph et al. (2004) Valproate decreases inositol biosynthesis. Biol Psychiatry 56:868-74
Ju, Shulin; Greenberg, Miriam L (2003) Valproate disrupts regulation of inositol responsive genes and alters regulation of phospholipid biosynthesis. Mol Microbiol 49:1595-603
Shamir, Alon; Shaltiel, Galit; Greenberg, Miriam L et al. (2003) The effect of lithium on expression of genes for inositol biosynthetic enzymes in mouse hippocampus; a comparison with the yeast model. Brain Res Mol Brain Res 115:104-10
Ding, Daobin; Greenberg, Miriam L (2003) Lithium and valproate decrease the membrane phosphatidylinositol/phosphatidylcholine ratio. Mol Microbiol 47:373-81

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