Lithium Regulation of Brain Protein Kinase C Substrates

Lenox, Robert H.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Mental Health (NIMH)
• Type: Research Project (R01)
• Project #: 1R01MH056247-01
• Application #: 2256433
• Study Section: Neuropharmacology and Neurochemistry Review Committee (NPNC)
• Project Start: 1996-09-30
• Project End: 1999-04-30
• Budget Start: 1996-09-30
• Budget End: 1997-04-30
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: University of Florida
• Department: Psychiatry
• Type: Schools of Medicine
• DUNS #: 073130411
• City: Gainesville
• State: FL
• Country: United States
• Zip Code: 32611

Publications

Wang, Le; Liu, Xingge; Lenox, Robert H (2002) Transcriptional regulation of mouse MARCKS promoter in immortalized hippocampal cells. Biochem Biophys Res Commun 292:969-79

Wang, L; Liu, X; Lenox, R H (2001) Transcriptional down-regulation of MARCKS gene expression in immortalized hippocampal cells by lithium. J Neurochem 79:816-25

Wang, L; Watson, D G; Lenox, R H (2000) Myristoylation alters retinoic acid-induced down-regulation of MARCKS in immortalized hippocampal cells. Biochem Biophys Res Commun 276:183-8

Lenox, R H; Hahn, C G (2000) Overview of the mechanism of action of lithium in the brain: fifty-year update. J Clin Psychiatry 61 Suppl 9:15-May

Watson, D G; Watterson, J M; Lenox, R H (1998) Sodium valproate down-regulates the myristoylated alanine-rich C kinase substrate (MARCKS) in immortalized hippocampal cells: a property of protein kinase C-mediated mood stabilizers. J Pharmacol Exp Ther 285:307-16