This application for a competing continuation of the Child Development Project (CDP) aims to test an empirical model of how chronic antisocial behavior develops in a longitudinal study of 585 boys and girls who have been followed annually since preschool and who will turn age 26 during the next five years. The CDP has been federally funded continuously since 1987 with cumulative attrition of less than I percent per year. The sample is diverse in background (17% African-American; 26% b0m in lowest SES groups; 3 geographic sites of Nashville, TN; Knoxville, TN; and Bloomington, IN) and varied in outcomes at the current age of 21 (36% treated for psychiatric disorders; 21% arrested; 37% suspended from school). 57 CDP publications support a transactional systems model of antisocial development that integrates biological and sociocultural context factors, child and adolescent life events, and acquired cognitive-emotional response patterns as mediators. Discoveries from the CDP include the first prospective demonstration that long-term adverse outcomes accrue from early physical maltreatment in a community sample and that social information processing patterns mediate these effects. Data will be collected annually for the next five years from participants, peers, romantic partners, offspring, observers, and archival records, toward the goal of assessing participants' level of participation, antisocial behavior, and competent prosocial behavior in relationships with other adults (peers, parents, authorities), romantic partners, and offspring. Major innovative aims are to: 1) test the interpersonal relationship domain-specificity of antisocial behavior and cognitive-emotional processes in young adulthood; 2) identify predictors of antisocial behavior in these three domains and to test hypotheses of an additive model, an interactive model, a life-experiences mediational model, a reciprocal-influence model, and a domain-specific model; 3) test the hypothesis that acquired, domain-specific social information-processing patterns mediate the effect of life experiences on antisocial outcomes; 4) test the generalizability of models across gender, ethnic, and cultural groups; 5) test the intergenerational transmission of behavior and cognitive-emotional processes; and 6) contribute to prevention practice and public policy by analyzing data in a way that addresses policy questions. This research will contribute both to basic theories of antisocial development and to prevention science and public policy.

National Institute of Health (NIH)
National Institute of Mental Health (NIMH)
Research Project (R01)
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Special Emphasis Panel (ZRG1-PDRP (02))
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Avenevoli, Shelli A
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Duke University
Schools of Arts and Sciences
United States
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Petersen, Isaac T; Lindhiem, Oliver; LeBeau, Brandon et al. (2018) Development of internalizing problems from adolescence to emerging adulthood: Accounting for heterotypic continuity with vertical scaling. Dev Psychol 54:586-599
Olson, Sheryl L; Davis-Kean, Pamela; Chen, Meichu et al. (2018) Mapping the Growth of Heterogeneous Forms of Externalizing Problem Behavior Between Early Childhood and Adolescence:A Comparison of Parent and Teacher Ratings. J Abnorm Child Psychol 46:935-950
Miller, Adam Bryant; Sheridan, Margaret A; Hanson, Jamie L et al. (2018) Dimensions of deprivation and threat, psychopathology, and potential mediators: A multi-year longitudinal analysis. J Abnorm Psychol 127:160-170
Goodnight, Jackson A; Bates, John E; Holtzworth-Munroe, Amy et al. (2017) Dispositional, demographic, and social predictors of trajectories of intimate partner aggression in early adulthood. J Consult Clin Psychol 85:950-965
Lansford, Jennifer E; Dodge, Kenneth A; Pettit, Gregory S et al. (2016) A Public Health Perspective on School Dropout and Adult Outcomes: A Prospective Study of Risk and Protective Factors From Age 5 to 27 Years. J Adolesc Health 58:652-8
Petersen, Isaac T; Bates, John E; Dodge, Kenneth A et al. (2016) Identifying an efficient set of items sensitive to clinical-range externalizing problems in children. Psychol Assess 28:598-612
Salvatore, Jessica E; Meyers, Jacquelyn L; Yan, Jia et al. (2015) Intergenerational continuity in parents' and adolescents' externalizing problems: The role of life events and their interaction with GABRA2. J Abnorm Psychol 124:709-28
Petersen, Isaac T; Bates, John E; Dodge, Kenneth A et al. (2015) Describing and predicting developmental profiles of externalizing problems from childhood to adulthood. Dev Psychopathol 27:791-818
Schwartz, David; Lansford, Jennifer E; Dodge, Kenneth A et al. (2015) Peer victimization during middle childhood as a lead indicator of internalizing problems and diagnostic outcomes in late adolescence. J Clin Child Adolesc Psychol 44:393-404
Chan, T W S; Bates, J E; Lansford, J E et al. (2014) Impulsivity and genetic variants in DRD2 and ANKK1 moderate longitudinal associations between sleep problems and overweight from ages 5 to 11. Int J Obes (Lond) 38:404-10

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