Research has show that continued high-risk sexual practices among people with HIV infection are related to psychological distress, maladaptive coping, difficulty disclosing HIV serostatus to sex partners, and problems coping with high-risk situations. Although HIV risk reduction interventions based on theories of behavior change have been successfully applied to populations vulnerable to becoming HIV infected, there have been no published studies reporting outcomes from theory- based sexual behavior change interventions for HIV seropositive men. This application requests support to develop and test the effects of an HIV risk reduction intervention designed for HIV seropositive men who continue to practice unsafe sex. The proposed research will begin with a 6-month period of formative study to interview 50 HIV seropositive men and women concerning factors that facilitate and interfere with maintenance of safer sex practices. We will also pilot test our assessment instruments and procedures during this period. Beginning in the second half of the first year of study, we will initiate recruitment of 300 HIV seropositive men who will be randomized to one of two experimental conditions: 91) a 12 session with 3 booster sessions experimental HIV risk reduction intervention based on social cognitive theory of coping and behavior change. The intervention will include five major components; coping skills training, social support network development, communication and self-disclosure skills enhancement, sexual risk reduction skills enhancement, and relapse prevention; or (2) 12 sessions with 3 reunion sessions contact matched control condition which will be structured as a closed support group. The study will specifically test the effectiveness of an intensive, theory-based HIV coping and risk reduction intervention for men who already know they are HIV infected. An emphasis will also be placed on communication and self-disclosure skills enhancement, and relapse prevention. Assessments collected at baseline, immediately following the intervention, and again at 3-months, 6-months, 9-months, and 12-months following the intervention will be used to determine relative intervention effects on mental health, social support, sexual communication and sexual behavior change outcomes. It is hypothesized that the cognitive behavioral skills intervention will result in increased coping and social support compared to the social support group condition, and that the cognitive behavioral intervention will demonstrate increased self-efficacy, intentions, and acts of disclosing HIV serostatus to sex partners, as well as reduction in high-risk sexual practices and increased condom use, over a longer period of time than the support groups. This research will therefore test the effects of a cognitive behavioral coping and risk reduction skills intervention that, if effective, could be readily implemented by health care clinics and AIDS service organizations providing services to HIV seropositive men.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
7R01MH057624-02
Application #
2675690
Study Section
Psychobiological, Biological, and Neurosciences Subcommittee (MHAI)
Program Officer
Pequegnat, Willo
Project Start
1997-09-30
Project End
2001-04-30
Budget Start
1998-08-01
Budget End
1999-04-30
Support Year
2
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Medical College of Wisconsin
Department
Psychiatry
Type
Schools of Medicine
DUNS #
073134603
City
Milwaukee
State
WI
Country
United States
Zip Code
53226
Kalichman, Seth C; Cherry, Charsey; White, Denise et al. (2007) Altering key characteristics of a disseminated effective behavioral intervention for HIV positive adults: the ""healthy relationships"" experience. J Prim Prev 28:145-53
Kalichman, Seth C (2005) The other side of the healthy relationships intervention: mental health outcomes and correlates of sexual risk behavior change. AIDS Educ Prev 17:66-75
Kalichman, Seth C; Rompa, David; Cage, Marjorie (2005) Group intervention to reduce HIV transmission risk behavior among persons living with HIV/AIDS. Behav Modif 29:256-85
Kalichman, Seth C; Gore-Felton, Cheryl; Benotsch, Eric et al. (2004) Trauma symptoms, sexual behaviors, and substance abuse: correlates of childhood sexual abuse and HIV risks among men who have sex with men. J Child Sex Abus 13:1-15
Kalichman, S C; Rompa, D (2003) HIV treatment adherence and unprotected sex practices in people receiving antiretroviral therapy. Sex Transm Infect 79:59-61
Kalichman, Seth C; DiMarco, Michael; Austin, James et al. (2003) Stress, social support, and HIV-status disclosure to family and friends among HIV-positive men and women. J Behav Med 26:315-32
Kalichman, Seth C; Weinhardt, Lance; DiFonzo, Kari et al. (2002) Sensation seeking and alcohol use as markers of sexual transmission risk behavior in HIV-positive men. Ann Behav Med 24:229-35
Kalichman, Seth C; Difonzo, Kari; Austin, James et al. (2002) Prospective study of emotional reactions to changes in HIV viral load. AIDS Patient Care STDS 16:113-20
Kalichman, Seth C; Benotsch, Eric G; Weinhardt, Lance S et al. (2002) Internet use among people living with HIV/AIDS: association of health information, health behaviors, and health status. AIDS Educ Prev 14:51-61
Kalichman, Seth C; Rompa, David; Luke, Webster et al. (2002) HIV transmission risk behaviours among HIV-positive persons in serodiscordant relationships. Int J STD AIDS 13:677-82

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