Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH060100-03
Application #
6392520
Study Section
Special Emphasis Panel (ZRG1-MDCN-5 (01))
Program Officer
Asanuma, Chiiko
Project Start
1999-08-01
Project End
2003-07-31
Budget Start
2001-08-01
Budget End
2002-07-31
Support Year
3
Fiscal Year
2001
Total Cost
$179,158
Indirect Cost
Name
University of Medicine & Dentistry of NJ
Department
Psychiatry
Type
Schools of Medicine
DUNS #
622146454
City
Piscataway
State
NJ
Country
United States
Zip Code
08854
Cowen, Daniel S; Takase, Luiz F; Fornal, Casimir A et al. (2008) Age-dependent decline in hippocampal neurogenesis is not altered by chronic treatment with fluoxetine. Brain Res 1228:14-9
Johnson-Farley, Nadine N; Patel, Khushboo; Kim, Deborah et al. (2007) Interaction of FGF-2 with IGF-1 and BDNF in stimulating Akt, ERK, and neuronal survival in hippocampal cultures. Brain Res 1154:40-9
Cowen, Daniel S (2007) Serotonin and neuronal growth factors - a convergence of signaling pathways. J Neurochem 101:1161-71
Johnson-Farley, Nadine N; Travkina, Tatyana; Cowen, Daniel S (2006) Cumulative activation of akt and consequent inhibition of glycogen synthase kinase-3 by brain-derived neurotrophic factor and insulin-like growth factor-1 in cultured hippocampal neurons. J Pharmacol Exp Ther 316:1062-9
Duann, Pu; Ho, Teh-Yuan; Desai, Bijal D et al. (2005) Mesangial cell apoptosis induced by stimulation of the adenosine A3 receptor: signaling and apoptotic events. J Investig Med 53:37-43
Johnson-Farley, Nadine N; Kertesy, Sylvia B; Dubyak, George R et al. (2005) Enhanced activation of Akt and extracellular-regulated kinase pathways by simultaneous occupancy of Gq-coupled 5-HT2A receptors and Gs-coupled 5-HT7A receptors in PC12 cells. J Neurochem 92:72-82
Cowen, Daniel S; Johnson-Farley, Nadine N; Travkina, Tatyana (2005) 5-HT receptors couple to activation of Akt, but not extracellular-regulated kinase (ERK), in cultured hippocampal neurons. J Neurochem 93:910-7
Lin, Stanley L; Johnson-Farley, Nadine N; Lubinsky, David R et al. (2003) Coupling of neuronal 5-HT7 receptors to activation of extracellular-regulated kinase through a protein kinase A-independent pathway that can utilize Epac. J Neurochem 87:1076-85
Lin, Stanley L; Le, Trung X; Cowen, Daniel S (2003) SptP, a Salmonella typhimurium type III-secreted protein, inhibits the mitogen-activated protein kinase pathway by inhibiting Raf activation. Cell Microbiol 5:267-75
Lin, Stanley L; Setya, Shilpy; Johnson-Farley, Nadine N et al. (2002) Differential coupling of 5-HT(1) receptors to G proteins of the G(i) family. Br J Pharmacol 136:1072-8

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