Abstract

We propose to develop a comprehensive database of simulated aMRI (3D) and fMRI datasets (4D) suitable for use in neuroinformatics tool validation studies. The project will be based upon an existing MRI simulator, MRISIM, which produces highly realistic MRI data, modeling the MRI signal generation, data acquisition process and noise propagation from first principles. The database aspects of the project will expand upon an existing prototype MRI image database and Web interface developed to allow uploading/downloading of MRI data. The proposed project has three specific aims:
Aim 1 : Enhance the MRI simulator for aMRI and fMRI applications.
Aim 2 : Create aMRI/fMRI databases of simulated/real data for tool validation.
Aim 3 : Enhance existing database/file format resources for a large-scale aMRI/fMRI database.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH067172-03
Application #
6801987
Study Section
Special Emphasis Panel (ZMH1-CRB-B (01))
Program Officer
Huerta, Michael F
Project Start
2002-09-20
Project End
2006-07-31
Budget Start
2004-08-01
Budget End
2005-07-31
Support Year
3
Fiscal Year
2004
Total Cost
$270,000
Indirect Cost

  Institution

Name
Mcgill University
Department
Type
DUNS #
205667090
City
Montreal
State
PQ
Country
Canada
Zip Code
H3 0-G4

  Publications

Bellec, Pierre; Perlbarg, Vincent; Evans, Alan C (2009) Bootstrap generation and evaluation of an fMRI simulation database. Magn Reson Imaging 27:1382-96