Anorexia Nervosa (AN) is a serious psychological condition with a prevalence estimated at 0.48% among adolescent females between 15-19 years. In adolescents, the illness severely affects physical, emotional, and social development. To date, there are no large-scale treatment studies of adolescents with AN. Smaller scale studies, however, suggest that a specific type of family-based treatment (FT) is an effective approach to adolescent onset AN. This multi-site study aims to compare this specific family therapy (FBT) with ego oriented individual psychotherapy (EOIT) to determine which treatment is more efficacious. The study has two specific aims: (1) To compare the relative efficacy of FBT and EOIT in adolescents with AN. We will specifically examine weight gain, psychological concerns about weight and shape and changes in family functioning. (2) To examine potential predictors, mediators and moderators of outcome. To accomplish these aims the following study is proposed: at two centers (60 per center), 120 adolescents between the ages of 12-18 meeting DSM-IV criteria for AN will be randomly assigned to one of two treatment groups: 1) FBT (manualized) for 24 planned patient hours for 12 months; or 2) EOIT (manualized) for 24 planned patient hours over 12 months. All patients will be followed for 1 year after the end of treatment. Assessment will occur at baseline, end of treatment, and six months and one-year follow-up. Primary outcome will be weight change. Secondary outcomes will be changes in weight and shape concerns as measured by the Eating Disorder Examination.
Goldschmidt, Andrea B; Crosby, Ross D; Cao, Li et al. (2018) Network analysis of pediatric eating disorder symptoms in a treatment-seeking, transdiagnostic sample. J Abnorm Psychol 127:251-264 |
Rienecke, Renee D; Accurso, Erin C; Lock, James et al. (2016) Expressed Emotion, Family Functioning, and Treatment Outcome for Adolescents with Anorexia Nervosa. Eur Eat Disord Rev 24:43-51 |
Rienecke, Renee D; Sim, Leslie; Lock, James et al. (2016) Patterns of expressed emotion in adolescent eating disorders. J Child Psychol Psychiatry 57:1407-1413 |
Goldschmidt, Andrea B; Accurso, Erin C; O'Brien, Setareh et al. (2016) The importance of loss of control while eating in adolescents with purging disorder. Int J Eat Disord 49:801-4 |
Hoste, Renee Rienecke; Lebow, Jocelyn; Le Grange, Daniel (2015) A bidirectional examination of expressed emotion among families of adolescents with bulimia nervosa. Int J Eat Disord 48:249-52 |
Byrne, Catherine E; Accurso, Erin C; Arnow, Katherine D et al. (2015) An exploratory examination of patient and parental self-efficacy as predictors of weight gain in adolescents with anorexia nervosa. Int J Eat Disord 48:883-8 |
Ciao, Anna C; Accurso, Erin C; Fitzsimmons-Craft, Ellen E et al. (2015) Family functioning in two treatments for adolescent anorexia nervosa. Int J Eat Disord 48:81-90 |
Accurso, Erin C; Fitzsimmons-Craft, Ellen E; Ciao, Anna C et al. (2015) From efficacy to effectiveness: comparing outcomes for youth with anorexia nervosa treated in research trials versus clinical care. Behav Res Ther 65:36-41 |
Elran-Barak, Roni; Sztainer, Maya; Goldschmidt, Andrea B et al. (2014) Family meal frequency among children and adolescents with eating disorders. J Adolesc Health 55:53-8 |
Elran-Barak, Roni; Accurso, Erin C; Goldschmidt, Andrea B et al. (2014) Eating patterns in youth with restricting and binge eating/purging type anorexia nervosa. Int J Eat Disord 47:878-83 |
Showing the most recent 10 out of 27 publications