The purpose of this study is to determine the effects of an aerobic interval training (AIT) protocol on the functional capacity (max VO2L), select mood states (Profile of Mood States -- POMS) and self assessment of sickness-related dysfunction (Sickness Impact Profile -- SIP) in cancer patients on chemotherapy with solid tumors of breast, colon, uterus, ovary and prostate at stage II, III, or IV. The research uses a two-group repeated measures (pre-, posttest) design. A sample of 90 subjects will be stratified by stage and randomized to experimental or control groups. Experimental subjects will enter the AIT protocol, exercising 3 times each week for 10 weeks; controls will maintain normal activities. Data on VO2L, POMS and SIP will be analyzed by (1) ANOVA for repeated measures pretest to posttest and (2) ANOCOVA to analyze the treatment (AIT protocol) effects with appropriate covariates. Study results will add to the knowledge independent living activities as long as possible. This research will provide data contributing to empirically-based guidelines to be used for adult cancer patients across disease stages.

Agency
National Institute of Health (NIH)
Institute
National Institute of Nursing Research (NINR)
Type
Research Project (R01)
Project #
5R01NR001825-02
Application #
3391687
Study Section
Nursing Research Study Section (NURS)
Project Start
1988-04-15
Project End
1991-03-31
Budget Start
1989-04-15
Budget End
1990-03-31
Support Year
2
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Ohio State University
Department
Type
Schools of Nursing
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210