Cardiovascular disease (CV) is a leading cause of morbidity and mortality in the United States. An increase of two to four times in the risk of heart disease is reported in persons with diabetes, regardless of whether they have type 1 or type 2 diabetes. In spite of the magnitude of this problem, few investigators have explored the effects of diabetes diagnosed during youth on the development of cardiovascular disease. The limited research that is available does suggest that cardiovascular risks, such as lipids and lipoproteins, are elevated for youth with type 1 diabetes compared with nondiabetic counterparts. Additionally, a decrease in heart rate variability has been documented for adolescents with type 1 diabetes, although no data were found regarding adolescents with type 2 diabetes. Greater numbers of adolescents are being diagnosed with type 2 diabetes, particularly in minority populations, secondary to sedentary lifestyle behaviors, obesity, and increased dietary fat consumption. The intent of this proposal is to describe differences in adolescents with type 1 and type 2 diabetes pertaining to cardiovascular risks, personal factors, and behavioral factors. In addition, we will examine relationships among these three sets of variables and determine how sociodemographic components influence each set of variables. A descriptive correlational design with a sample of 100 adolescents with type 1 diabetes and 100 adolescents with type 2 diabetes will be used to investigate cardiovascular risks, as well as predisposing factors such as exercise beliefs, level of physical activity, dietary practices, self-competence, and body mass index. Sociodemographic variables such as race, gender, socioeconomic status, family structure and history will be included. Determining variations in cardiovascular risks and predisposing factors for youth with type 1 versus type 2 diabetes is essential prior to designing interventions that promote positive health outcomes, ultimately control escalating costs for diabetes care, and minimize adverse effects on health status and well being. This investigation is particularly relevant given the limited research on cardiovascular risks in adolescents with type 2 diabetes.

Agency
National Institute of Health (NIH)
Institute
National Institute of Nursing Research (NINR)
Type
Research Project (R01)
Project #
5R01NR007719-02
Application #
6393123
Study Section
Nursing Research Study Section (NURS)
Program Officer
Armstrong, Nell
Project Start
2000-09-20
Project End
2005-05-31
Budget Start
2001-06-01
Budget End
2002-05-31
Support Year
2
Fiscal Year
2001
Total Cost
$284,818
Indirect Cost
Name
University of Illinois at Chicago
Department
Type
Schools of Nursing
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612
Faulkner, Melissa Spezia (2010) Cardiovascular fitness and quality of life in adolescents with type 1 or type 2 diabetes. J Spec Pediatr Nurs 15:307-16
Faulkner, Melissa Spezia; Quinn, Lauretta; Fritschi, Cynthia (2010) Microalbuminuria and heart rate variability in adolescents with diabetes. J Pediatr Health Care 24:34-41
Shaibi, Gabriel Q; Michaliszyn, Sara B; Fritschi, Cynthia et al. (2009) Type 2 diabetes in youth: A phenotype of poor cardiorespiratory fitness and low physical activity. Int J Pediatr Obes :1-6
Michaliszyn, Sara Fleet; Shaibi, Gabriel Q; Quinn, Lauretta et al. (2009) Physical fitness, dietary intake, and metabolic control in adolescents with type 1 diabetes. Pediatr Diabetes 10:389-94
Shaibi, Gabriel Q; Faulkner, Melissa S; Weigensberg, Marc J et al. (2008) Cardiorespiratory fitness and physical activity in youth with type 2 diabetes. Pediatr Diabetes 9:460-3
Johns, Carla; Faulkner, Melissa Spezia; Quinn, Lauretta (2008) Characteristics of adolescents with type 1 diabetes who exhibit adverse outcomes. Diabetes Educ 34:874-85
Faulkner, Melissa Spezia; Chao, Wei-Hsun; Kamath, Savitri K et al. (2006) Total homocysteine, diet, and lipid profiles in type 1 and type 2 diabetic and nondiabetic adolescents. J Cardiovasc Nurs 21:47-55
Faulkner, Melissa Spezia; Quinn, Laurie; Rimmer, James H et al. (2005) Cardiovascular endurance and heart rate variability in adolescents with type 1 or type 2 diabetes. Biol Res Nurs 7:16-29