Abstract

Statement of Problem: Stem cell transplant (SCT), the curative therapy of choice for many malignancies that require high-dose radiation or chemotherapy, is an intensive, multi-phase procedure with many risks, including death, Recent studies suggest that SCT is a particularly stressful procedure for adolescents and young adults (AYA) and may result in significant short-and long-term decrements in quality of life. Broad Objective: To develop and test the efficacy of a therapeutic music video (TMV) intervention aimed at increasing resilience and quality of life of AYA undergoing SCT.
Specific Aims : To determine whether AYA assigned to the TMV intervention, compared to a low dose control group, experience: 1) reduced illness-related distress; 2) improved family environment; 3) increased perceived social support; 4) improved coping; 5) greater derived meaning; 6) increased resilience and quality of life. Secondary aims include qualitatively examining the self-reported benefits of the TMV intervention and the low-dose books-on-tape intervention for AYA and their family caregivers. Design and Method: Randomized, controlled trial methods will be used for this multi-site study. Approximately 130 AYA between 11 and 24 years of age undergoing SCT for cancer will be assigned to either the TMV intervention group or to a low dose control group. Intervention participants will be guided by a board certified music therapist to develop a music video based on their experiences with cancer over the course of 6 sessions. Low dose control participants will take part in a 6 session books-on-tape program. Outcomes data will be collected at multiple time points during the patient's hospitalization and at 100 days post-transplant using self-report inventories assessing the constructs described in the Specific Aims. Group differences will be examined using a linear mixed models approach and qualitative data will be analyzed using an adaptation of Colaizzi's method of phenomenological analysis.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Nursing Research (NINR)
Type
Research Project (R01)
Project #
5R01NR008583-02
Application #
7092075
Study Section
Nursing Science: Children and Families Study Section (NSCF)
Program Officer
Marden, Susan F
Project Start
2005-07-07
Project End
2009-04-30
Budget Start
2006-05-08
Budget End
2007-04-30
Support Year
2
Fiscal Year
2006
Total Cost
$467,681
Indirect Cost

  Institution

Name
Indiana University-Purdue University at Indianapolis
Department
Type
Schools of Nursing
DUNS #
603007902
City
Indianapolis
State
IN
Country
United States
Zip Code
46202

  Publications

Haase, Joan E; Kintner, Eileen K; Robb, Sheri L et al. (2017) The Resilience in Illness Model Part 2: Confirmatory Evaluation in Adolescents and Young Adults With Cancer. Cancer Nurs 40:454-463
Hendricks-Ferguson, Verna L; Barnes, Yvonne J; Cherven, Brooke et al. (2017) Stories and Music for Adolescent/Young Adult Resilience During Transplant Partnerships: Strategies to Support Academic-Clinical Nurse Collaborations in Behavioral Intervention Studies. Clin Nurse Spec 31:195-200
Phillips-Salimi, Celeste R; Robb, Sheri L; Monahan, Patrick O et al. (2014) Perceptions of communication, family adaptability and cohesion: a comparison of adolescents newly diagnosed with cancer and their parents. Int J Adolesc Med Health 26:19-26
Kelly, Katherine P; Hooke, Mary C; Ruccione, Kathleen et al. (2014) Children's Oncology Group nursing research framework. Semin Oncol Nurs 30:17-25
Robb, Sheri L; Burns, Debra S; Stegenga, Kristin A et al. (2014) Randomized clinical trial of therapeutic music video intervention for resilience outcomes in adolescents/young adults undergoing hematopoietic stem cell transplant: a report from the Children's Oncology Group. Cancer 120:909-17
Roll, Lona; Stegenga, Kristin; Hendricks-Ferguson, Verna et al. (2013) Engaging nurses in research for a randomized clinical trial of a behavioral health intervention. Nurs Res Pract 2013:183984
Docherty, Sharron L; Robb, Sheri L; Phillips-Salimi, Celeste et al. (2013) Parental perspectives on a behavioral health music intervention for adolescent/young adult resilience during cancer treatment: report from the children's oncology group. J Adolesc Health 52:170-8
Hendricks-Ferguson, Verna L; Cherven, Brooke O; Burns, Debra S et al. (2013) Recruitment strategies and rates of a multi-site behavioral intervention for adolescents and young adults with cancer. J Pediatr Health Care 27:434-42
Robb, Sheri L; Burns, Debra S; Docherty, Sharron L et al. (2011) Ensuring treatment fidelity in a multi-site behavioral intervention study: implementing NIH Behavior Change Consortium recommendations in the SMART trial. Psychooncology 20:1193-201
Robb, Sheri L; Burns, Debra S; Carpenter, Janet S (2011) Reporting guidelines for music-based interventions. J Health Psychol 16:342-52

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