: The HIV contraction rate for Latina women in the U.S. is six times the rate for non-Latina, White women. Latinas are suffering disparate negative consequences from substance use disorders, including intimate partner violence, incarceration, homelessness, and medical ailments. Our long-term goal is to reduce the incidence of HIV and substance abuse related health disparities among Latinas. The objective of this application, which is a significant step in pursuit of this goal, is to determine how substance use (both licit and illicit) and HIV risk behavior trajectories of a community-based sample of Latina mothers and daughters are influenced by changes in familial mechanisms (mother-daughter acoplamiento or attachment), cultural processes, and other social determinants of substance abuse and HIV risk behaviors over time. The study design involves four waves of data collection. Baseline data were collected in a cross-sectional pilot study of intergenerational drug use and HIV risk behaviors among Latina mothers and daughters funded by NIDA (R24DA014260, PI: Mario De La Rosa, Ph.D.). Three new longitudinal assessments are proposed to follow-up on baseline assessment. The first new follow-up assessment will be spaced approximately 5 years from the original study's baseline assessment. The remaining two follow-up assessments will occur 1 year from the preceding follow-up assessment.
Our first aim i s to determine the influence of cultural and social determinants on trajectories of change for substance use and HIV risk behaviors among a community-based sample of Latina mothers and daughters. The working hypothesis is that Latina mothers and daughters who experience (1) more acculturation to U.S. culture;(2) poorer socioeconomic conditions;(3) a loss of interpersonal supports;(4) less religious involvement;(5) involvement with the criminal justice system;(6) intimate partner violence;(7) greater employment, relationship, and/or residential related chronic stress;or (8) declining mental health and medical status since their baseline assessment will exhibit either an increase in or maintenance of high rates of substance use and HIV risk behaviors over the 7 year assessment time period.
Our second aim i s to determine the influence of mother-daughter attachment on trajectories of change for substance use and HIV risk behaviors. Latina mothers and daughters who either increase their levels of attachment or maintain consistently high levels of attachment will report reduced or consistently lower levels of substance use and HIV risk behaviors over a 7 year time period.
Our third aim i s to determine the moderating role of mother-daughter attachment on associations between experiences of detrimental social determinants and trajectories of change for substance use and HIV risk behaviors.

Public Health Relevance

Relevance to public health: This study will fundamentally advance culturally and empirically based substance abuse and HIV/AIDS prevention strategies for adult Latinas in the U.S. The lack of such strategies is a major public health problem because, until they become available, it is likely that there will be little if any reduction in the HIV/AIDS and substance abuse health disparities affecting Latinas. In the worst-case analysis, there could even be significant increases in substance use problems and HIV/AIDS cases in the U.S., given that Latinos are the largest and fastest growing minority group in the U.S.

National Institute of Health (NIH)
National Institute of Nursing Research (NINR)
Research Project (R01)
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Special Emphasis Panel (ZMD1-PA (R4))
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Hardy, Lynda R
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Florida International University
Social Sciences
Schools of Social Work
United States
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De La Rosa, Mario; Huang, Hui; Brook, Judith S et al. (2018) Sociocultural determinants of substance misuse among adult Latinas of Caribbean and South and Central American descent: A longitudinal study of a community-based sample. J Ethn Subst Abuse 17:303-323
Rojas, Patria; Li, Tan; Ravelo, Gira J et al. (2017) Correlates of Cervical Cancer Screening Among Adult Latino Women: A 5-Year Follow-Up. World Med Health Policy 9:239-254
Kanamori, Mariano; Weissman, Jessica; De La Rosa, Mario et al. (2016) Latino Mother/Daughter Dyadic Attachment as a Mediator for Substance Use Disorder and Emotional Abuse. J Immigr Minor Health 18:896-903
Lopez-Quintero, Catalina; Rojas, Patria; Dillon, Frank R et al. (2016) HIV testing practices among Latina women at risk of getting infected: a five-year follow-up of a community sample in South Florida. AIDS Care 28:137-46
Concha, Maritza; Sanchez, Mariana; Rojas, Patria et al. (2016) Differences in Acculturation and Trajectories of Anxiety and Alcohol Consumption Among Latina Mothers and Daughters in South Florida. J Immigr Minor Health 18:886-95
De La Rosa, Mario; Huang, Hui; Rojas, Patria et al. (2015) Influence of mother-daughter attachment on substance use: a longitudinal study of a Latina community-based sample. J Stud Alcohol Drugs 76:307-16
Beaulaurier, Richard; Fortuna, Karen; Lind, Danielle et al. (2014) Attitudes and stereotypes regarding older women and HIV risk. J Women Aging 26:351-68
Rojas, Patria; Dillon, Frank R; Ravelo, Gira J et al. (2013) Non-medical prescription sedative use among adult Latina mothers and daughters. J Psychoactive Drugs 45:329-39
Cohen, David; Dillon, Frank R; Gladwin, Hugh et al. (2013) American parents' willingness to prescribe psychoactive drugs to children: a test of cultural mediators. Soc Psychiatry Psychiatr Epidemiol 48:1873-87