Temporal bones will be acquired from human subjects who had experienced disorders of the peripheral auditory and/or vestibular system, middle ear, bony labyrinth, or facial nerve. The specimens will derive predominantly from the morgues of the Harvard teaching hospitals, the National Temporal Bone Bank Program), and from foreign countries (Costa Rica, Chile, and Switzerland). The temporal bones will be prepared for light microscopic study by the method of fixation, decalcification, embedding in celloidin, serial sectioning, staining, and mounting. The pathological changes will be identified and quantified as to severity and spatial distribution and correlations made of the temporal bone findings with clinical data. General medical and otologic histories and autopsy findings will be available on all subjects, and most of them will have had detailed audiometric and/or vestibular function tests. It can be anticipated that these studies will further our knowledge of the pathology of deafness, vertigo, and facial palsy, and will lead to more rational therapeutic approaches to otologic disease.
| Djeric, D; Schuknecht, H F (1989) Hensen's cell cyst of the organ of Corti. Acta Otolaryngol 108:55-61 |
| Ramadan, H H; Schuknecht, H F (1989) Is there a conductive type of presbycusis? Otolaryngol Head Neck Surg 100:30-4 |
| Merchant, S N; Schuknecht, H F (1988) Vestibular atelectasis. Ann Otol Rhinol Laryngol 97:565-76 |
| Pauler, M; Schuknecht, H F; White, J A (1988) Atrophy of the stria vascularis as a cause of sensorineural hearing loss. Laryngoscope 98:754-9 |
| Schuknecht, H F; Reisser, C (1988) The morphologic basis for perilymphatic gushers and oozers. Adv Otorhinolaryngol 39:1-12 |
| Quijano, M; Schuknecht, H F; Otte, J (1988) Temporal bone pathology associated with intracranial abscess. ORL J Otorhinolaryngol Relat Spec 50:2-31 |
| Quijano, M L; Schuknecht, H F; Bradley, D H (1988) The incidence of fibrosis in the vestibular ganglia in Meniere's disease. Arch Otorhinolaryngol 245:133-5 |
| Suzuka, Y; Schuknecht, H F (1988) Retrograde cochlear neuronal degeneration in human subjects. Acta Otolaryngol Suppl 450:1-20 |
| Hashimoto, S; Schuknecht, H F (1987) Progressive hearing loss from strial dysplasia. Ann Otol Rhinol Laryngol 96:229-31 |
| Okuno, T; Sando, I (1987) Localization, frequency, and severity of endolymphatic hydrops and the pathology of the labyrinthine membrane in Meniere's disease. Ann Otol Rhinol Laryngol 96:438-45 |
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