A four-fold program of research in communication in aphasia will be pursued: First, experimental psycholinguistics studies will attempt to characterize the disruption of mechanisms underlying syntactic processing in aphasia and to detail the ability of aphasic patients to plan utterances on-line, both in terms of structure and semantic content. Also included will be an attempt to train aphasic patients to produce sentences and to determine whether or not production training for any given construction type also benefits comprehension for sentences embodying that construction. Second, the ability of aphasic patients to use and comprehend a range of symbol systems will be probed; results of this study will be used to inform an alternative form of visual communication therapy for global aphasics. Third, an examination of the pragmatics of communication in aphasia will determine the role of gesture in conveying information and the capacity of aphasic patients to utilize pragmatic devices such as those involved in bridging given and new information. Finally, a concerted set of studies will delineate the contribution of the right hemisphere to the processing of linguistic materials and to the comprehension of other non-linguistic vehicles of communication such as emotional expressions. This program of study should yield a fuller picture of aphasic communication, since it will delineate spared as well as damaged facets of communicative capacities.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS011408-13
Application #
3394464
Study Section
Communication Sciences and Disorders (CMS)
Project Start
1976-09-01
Project End
1986-08-31
Budget Start
1985-09-01
Budget End
1986-08-31
Support Year
13
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Boston University
Department
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
Prather, P; Zurif, E; Stern, C et al. (1992) Slowed lexical access in nonfluent aphasia: a case study. Brain Lang 43:336-48
Prather, P; Shapiro, L; Zurif, E et al. (1991) Real-time examinations of lexical processing in aphasics. J Psycholinguist Res 20:271-81
Zurif, E; Swinney, D; Fodor, J A (1991) An evaluation of assumptions underlying the single-patient-only position in neuropsychological research: a reply. Brain Cogn 16:198-210
Kaplan, J A; Brownell, H H; Jacobs, J R et al. (1990) The effects of right hemisphere damage on the pragmatic interpretation of conversational remarks. Brain Lang 38:315-33
Ostrove, J M; Simpson, T; Gardner, H (1990) Beyond scripts: a note on the capacity of right hemisphere-damaged patients to process social and emotional content. Brain Cogn 12:144-54
Brownell, H H; Simpson, T L; Bihrle, A M et al. (1990) Appreciation of metaphoric alternative word meanings by left and right brain-damaged patients. Neuropsychologia 28:375-83
Canseco-Gonzalez, E; Shapiro, L P; Zurif, E B et al. (1990) Predicate-argument structure as a link between linguistic and nonlinguistic representations. Brain Lang 39:391-404
Shapiro, L P; Levine, B A (1990) Verb processing during sentence comprehension in aphasia. Brain Lang 38:21-47
Shapiro, L P; Zurif, E; Carey, S et al. (1989) Comprehension of lexical subcategory distinctions by aphasic patients: proper/common and mass/count nouns. J Speech Hear Res 32:481-8
Zurif, E B; Gardner, H; Brownell, H H (1989) The case against the case against group studies. Brain Cogn 10:237-55

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