Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
3R01NS013792-09S1
Application #
3395316
Study Section
Communication Sciences and Disorders (CMS)
Project Start
1977-09-01
Project End
1991-06-30
Budget Start
1986-12-01
Budget End
1987-06-30
Support Year
9
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Cammer, W; Zhang, H (1993) Lectin binding by macroglial and microglial cells in the brains of young normal and myelin-deficient (md) mutant rats. Glycobiology 3:627-31
Huang, M; Dulon, D; Schacht, J (1990) Outer hair cells as potential targets of inflammatory mediators. Ann Otol Rhinol Laryngol Suppl 148:35-8
Forge, A; Zajic, G; Davies, S et al. (1989) Gentamicin alters membrane structure as shown by freeze-fracture of liposomes. Hear Res 37:129-39
Huang, M Y; Schacht, J (1989) Drug-induced ototoxicity. Pathogenesis and prevention. Med Toxicol Adverse Drug Exp 4:452-67
Dulon, D; Zajic, G; Aran, J M et al. (1989) Aminoglycoside antibiotics impair calcium entry but not viability and motility in isolated cochlear outer hair cells. J Neurosci Res 24:338-46
Dulon, D; Zajic, G; Schacht, J (1989) Photo-induced irreversible shortening and swelling of isolated cochlear outer hair cells. Int J Radiat Biol 55:1007-14
Riaz, M; Weiner, N D; Schacht, J (1989) Separation of liposome populations differing in phosphoinositide content by chromatography on immobilized neomycin. J Pharm Sci 78:172-5
Henley 3rd, C M; Mahran, L G; Schacht, J (1988) Inhibition of renal ornithine decarboxylase by aminoglycoside antibiotics in vitro. Biochem Pharmacol 37:1679-82
Henley 3rd, C M; Schacht, J (1988) Pharmacokinetics of aminoglycoside antibiotics in blood, inner-ear fluids and tissues and their relationship to ototoxicity. Audiology 27:137-46
Williams, S E; Zenner, H P; Schacht, J (1987) Three molecular steps of aminoglycoside ototoxicity demonstrated in outer hair cells. Hear Res 30:11-8

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