Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS019988-12
Application #
2263731
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Program Officer
Jacobs, Margaret
Project Start
1983-09-10
Project End
1998-06-30
Budget Start
1995-07-01
Budget End
1998-06-30
Support Year
12
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Washington University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Rothman, S M (1999) Mutations of the mitochondrial genome: clinical overview and possible pathophysiology of cell damage. Biochem Soc Symp 66:111-22
Werth, J L; Park, T S; Silbergeld, D L et al. (1998) Excitotoxic swelling occurs in oxygen and glucose deprived human cortical slices. Brain Res 782:248-54
Handran, S D; Werth, J L; DeVivo, D C et al. (1997) Mitochondrial morphology and intracellular calcium homeostasis in cytochrome oxidase-deficient human fibroblasts. Neurobiol Dis 3:287-98
Yamada, K A; Turetsky, D M (1996) Allosteric interactions between cyclothiazide and AMPA/kainate receptor antagonists. Br J Pharmacol 117:1663-72
Holland, K D; Mathews, G C; Bolos-Sy, A M et al. (1995) Dual modulation of the gamma-aminobutyric acid type A receptor/ionophore by alkyl-substituted gamma-butyrolactones. Mol Pharmacol 47:1217-23
Dugan, L L; Sensi, S L; Canzoniero, L M et al. (1995) Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate. J Neurosci 15:6377-88
White, L E; Hodges, H D; Carnes, K M et al. (1994) Colocalization of excitatory and inhibitory neurotransmitter markers in striatal projection neurons in the rat. J Comp Neurol 339:328-40
Dubinsky, J M (1993) Effects of calcium chelators on intracellular calcium and excitotoxicity. Neurosci Lett 150:129-32
Rothman, S M; Yamada, K A; Lancaster, N (1993) Nordihydroguaiaretic acid attenuates NMDA neurotoxicity--action beyond the receptor. Neuropharmacology 32:1279-88
Yamada, K A; Tang, C M (1993) Benzothiadiazides inhibit rapid glutamate receptor desensitization and enhance glutamatergic synaptic currents. J Neurosci 13:3904-15

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