Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
3R01NS021122-08S1
Application #
3401938
Study Section
Neurology B Subcommittee 2 (NEUB)
Project Start
1987-09-01
Project End
1995-07-31
Budget Start
1993-08-01
Budget End
1994-07-31
Support Year
8
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Yates, Jennifer R; Heyes, Melvyn P; Blight, Andrew R (2006) 4-chloro-3-hydroxyanthranilate reduces local quinolinic acid synthesis, improves functional recovery, and preserves white matter after spinal cord injury. J Neurotrauma 23:866-81
Jaeger, C B; Blight, A R (1997) Spinal cord compression injury in guinea pigs: structural changes of endothelium and its perivascular cell associations after blood-brain barrier breakdown and repair. Exp Neurol 144:381-99
Blight, A R; Leroy Jr, E C; Heyes, M P (1997) Quinolinic acid accumulation in injured spinal cord: time course, distribution, and species differences between rat and guinea pig. J Neurotrauma 14:89-98
Gruner, J A; Yee, A K; Blight, A R (1996) Histological and functional evaluation of experimental spinal cord injury: evidence of a stepwise response to graded compression. Brain Res 729:90-101
Cohen, T I; Weinberg, R J; Blight, A R (1996) Intrathecal infusion of the nitric oxide synthase inhibitor N-methyl L-arginine after experimental spinal cord injury in guinea pigs. J Neurotrauma 13:361-9
Blight, A R; Cohen, T I; Saito, K et al. (1995) Quinolinic acid accumulation and functional deficits following experimental spinal cord injury. Brain 118 ( Pt 3):735-52
Blight, A R (1994) Effects of silica on the outcome from experimental spinal cord injury: implication of macrophages in secondary tissue damage. Neuroscience 60:263-73
Blight, A R (1993) Remyelination, revascularization, and recovery of function in experimental spinal cord injury. Adv Neurol 59:91-104
Blight, A R; Saito, K; Heyes, M P (1993) Increased levels of the excitotoxin quinolinic acid in spinal cord following contusion injury. Brain Res 632:314-6
Blight, A R (1992) Macrophages and inflammatory damage in spinal cord injury. J Neurotrauma 9 Suppl 1:S83-91

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