Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
3R01NS021466-03S1
Application #
3402599
Study Section
Neurology B Subcommittee 1 (NEUB)
Project Start
1984-12-01
Project End
1988-02-29
Budget Start
1987-12-01
Budget End
1988-02-29
Support Year
3
Fiscal Year
1988
Total Cost
Indirect Cost
Name
St. Luke's Roosevelt Hosp Center (New York)
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10025
Bourdette, D N; Chou, Y K; Whitham, R H et al. (1998) Immunity to T cell receptor peptides in multiple sclerosis. III. Preferential immunogenicity of complementarity-determining region 2 peptides from disease-associated T cell receptor BV genes. J Immunol 161:1034-44
Bourdette, D N; Whitham, R H; Chou, Y K et al. (1994) Immunity to TCR peptides in multiple sclerosis. I. Successful immunization of patients with synthetic V beta 5.2 and V beta 6.1 CDR2 peptides. J Immunol 152:2510-9
Chou, Y K; Jones, R E; Bourdette, D et al. (1994) Human myelin basic protein (MBP) epitopes recognized by mouse MBP-selected T cell lines from multiple sclerosis patients. J Neuroimmunol 49:45-50
Satyanarayana, K; Chou, Y K; Bourdette, D et al. (1993) Epitope specificity and V gene expression of cerebrospinal fluid T cells specific for intact versus cryptic epitopes of myelin basic protein. J Neuroimmunol 44:57-67
Vandenbark, A A; Bourdette, D N; Whitham, R et al. (1993) T-cell receptor peptide therapy in EAE and MS. Clin Exp Rheumatol 11 Suppl 8:S51-3
Vandenbark, A A; Hashim, G; Offner, H (1993) TCR peptide therapy in autoimmune diseases. Int Rev Immunol 9:251-76
Vandenbark, A A; Chou, Y K; Bourdette, D N et al. (1992) T cell receptor peptide therapy for autoimmune disease. J Autoimmun 5 Suppl A:83-92
Vainiene, M; Gold, D P; Celnik, B et al. (1992) Common sequence on distinct V beta genes defines a protective idiotope in experimental encephalomyelitis. J Neurosci Res 31:413-20
Offner, H; Vainiene, M; Gold, D P et al. (1992) Characterization of the immune response to a secondary encephalitogenic epitope of basic protein in Lewis rats. I. T cell receptor peptide regulation of T cell clones expressing cross-reactive V beta genes. J Immunol 148:1706-11
Vandenbark, A A; Vainiene, M; Celnik, B et al. (1992) TCR peptide therapy decreases the frequency of encephalitogenic T cells in the periphery and the central nervous system. J Neuroimmunol 39:251-60

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