Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS021501-12
Application #
2264199
Study Section
Physiology Study Section (PHY)
Project Start
1984-12-01
Project End
1999-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Physiology
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Bai, Jun-Ping; Moeini-Naghani, Iman; Zhong, Sheng et al. (2017) Current carried by the Slc26 family member prestin does not flow through the transporter pathway. Sci Rep 7:46619
Jensen, Katrine Hommelhoff; Sigworth, Fred J; Brandt, Sami Sebastian (2016) Removal of Vesicle Structures From Transmission Electron Microscope Images. IEEE Trans Image Process 25:540-52
Jensen, Katrine Hommelhoff; Brandt, Sami Sebastian; Shigematsu, Hideki et al. (2016) Statistical modeling and removal of lipid membrane projections for cryo-EM structure determination of reconstituted membrane proteins. J Struct Biol 194:49-60
Sigworth, Fred J (2016) Principles of cryo-EM single-particle image processing. Microscopy (Oxf) 65:57-67
Dvornek, Nicha C; Sigworth, Fred J; Tagare, Hemant D (2015) SubspaceEM: A fast maximum-a-posteriori algorithm for cryo-EM single particle reconstruction. J Struct Biol 190:200-14
Singh, Satinder K; Sigworth, Fred J (2015) Cryo-EM: Spinning the Micelles Away. Structure 23:1561
Tagare, Hemant D; Kucukelbir, Alp; Sigworth, Fred J et al. (2015) Directly reconstructing principal components of heterogeneous particles from cryo-EM images. J Struct Biol 191:245-62
Kucukelbir, Alp; Sigworth, Fred J; Tagare, Hemant D (2014) Quantifying the local resolution of cryo-EM density maps. Nat Methods 11:63-5
Liu, Yunhui; Sigworth, Fred J (2014) Automatic cryo-EM particle selection for membrane proteins in spherical liposomes. J Struct Biol 185:295-302
Shigematsu, H; Sigworth, F J (2013) Noise models and cryo-EM drift correction with a direct-electron camera. Ultramicroscopy 131:61-9

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