Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
3R01NS022941-06S1
Application #
3405784
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1986-08-01
Project End
1994-11-30
Budget Start
1992-12-01
Budget End
1993-11-30
Support Year
6
Fiscal Year
1993
Total Cost
Indirect Cost

  Institution

Name
University of California Davis
Department
Type
Schools of Earth Sciences/Natur
DUNS #
094878337
City
Davis
State
CA
Country
United States
Zip Code
95618

  Publications

Kim, J; McNamee, M G (1998) Topological disposition of Cys 222 in the alpha-subunit of nicotinic acetylcholine receptor analyzed by fluorescence-quenching and electron paramagnetic resonance measurements. Biochemistry 37:4680-6
Butler, D H; Lasalde, J A; Butler, J K et al. (1997) Mouse-Torpedo chimeric alpha-subunit used to probe channel-gating determinants on the nicotinic acetylcholine receptor primary sequence. Cell Mol Neurobiol 17:13-33
Ortiz-Miranda, S I; Lasalde, J A; Pappone, P A et al. (1997) Mutations in the M4 domain of the Torpedo californica nicotinic acetylcholine receptor alter channel opening and closing. J Membr Biol 158:17-30
Tamamizu, S; Butler, D H; Lasalde, J A et al. (1996) Effects of antibody binding on structural transitions of the nicotinic acetylcholine receptor. Biochemistry 35:11773-81
Vibat, C R; Lasalde, J A; McNamee, M G et al. (1995) Differential desensitization properties of rat neuronal nicotinic acetylcholine receptor subunit combinations expressed in Xenopus laevis oocytes. Cell Mol Neurobiol 15:411-25
Tamamizu, S; Todd, A P; McNamee, M G (1995) Mutations in the M1 region of the nicotinic acetylcholine receptor alter the sensitivity to inhibition by quinacrine. Cell Mol Neurobiol 15:427-38
Lee, Y H; Li, L; Lasalde, J et al. (1994) Mutations in the M4 domain of Torpedo californica acetylcholine receptor dramatically alter ion channel function. Biophys J 66:646-53
Eterovic, V A; Hann, R M; Ferchmin, P A et al. (1993) Diterpenoids from Caribbean gorgonians act as noncompetitive inhibitors of the nicotinic acetylcholine receptor. Cell Mol Neurobiol 13:99-110
Eterovic, V A; Li, L; Ferchmin, P A et al. (1993) The ion channel of muscle and electric organ acetylcholine receptors: differing affinities for noncompetitive inhibitors. Cell Mol Neurobiol 13:111-21
Li, L; Lee, Y H; Pappone, P et al. (1992) Site-specific mutations of nicotinic acetylcholine receptor at the lipid-protein interface dramatically alter ion channel gating. Biophys J 62:61-3

Showing the most recent 10 out of 16 publications