The specific aim of this follow-up study is to assess the significance of previously reported factors determining neuropsychological development of higher language, verbal and non-verbal cognitive functions and lower sensory and motor functions in a 6 year follow-up study of 295 children and young adults with hydrocephalus and in 149 normal control children. In view of the current lack of any longitudinal neuropsychological follow-up studies of hydrocephalics, this study will provide unique opportunities to investigate the dynamics of cerebral development and outcome in hydrocephalus. The findings of this study will have conceivably important practical implications for future assessment and treatment of hydrocephalics, and other children and young adults with diffuse brain insults. Finally, the findings of this study will provide bases for further elucidation of principles underlying organization, disorganization and reorganization of human brain function.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS024344-02
Application #
3408853
Study Section
Human Development and Aging Subcommittee 1 (HUD)
Project Start
1987-02-01
Project End
1990-01-31
Budget Start
1988-02-01
Budget End
1990-01-31
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
Schools of Education
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Berker, E; Goldstein, G; Lorber, J et al. (1992) Reciprocal neurological developments of twins discordant for hydrocephalus. Dev Med Child Neurol 34:623-32
Berker, E; Smith, A (1988) Diaschisis, site, time and other factors in raven performances of adults with focal cerebral lesions. Int J Neurosci 38:267-85