Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
2R01NS025519-07
Application #
2265565
Study Section
Special Emphasis Panel (ZRG2-IVP (02))
Project Start
1988-02-01
Project End
2001-04-30
Budget Start
1996-08-01
Budget End
1997-04-30
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Allegheny University of Health Sciences
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19129
Blankenhorn, E P; Butterfield, R J; Rigby, R et al. (2000) Genetic analysis of the influence of pertussis toxin on experimental allergic encephalomyelitis susceptibility: an environmental agent can override genetic checkpoints. J Immunol 164:3420-5
Teuscher, C; Butterfield, R J; Ma, R Z et al. (1999) Sequence polymorphisms in the chemokines Scya1 (TCA-3), Scya2 (monocyte chemoattractant protein (MCP)-1), and Scya12 (MCP-5) are candidates for eae7, a locus controlling susceptibility to monophasic remitting/nonrelapsing experimental allergic encephalomy J Immunol 163:2262-6
Bourque, M M; Martin, A M; Desquennes-Clark, L et al. (1996) Possible mechanism for the TCR beta-chain associated EAE resistance of LER rats. J Neurosci Res 45:714-22
Blankenhorn, E P; Stranford, S A; Martin, A M et al. (1995) Cloning of myelin basic protein-reactive T cells from the experimental allergic encephalomyelitis-resistant rat strain, LER. J Neuroimmunol 59:173-83
Livingstone, K D; Sudweeks, J D; Blankenhorn, E P et al. (1995) Susceptibility to actively-induced murine experimental allergic encephalomyelitis is not linked to genes of the T cell receptor or CD3 complexes. Autoimmunity 21:195-201
Wardell, B B; Michael, S D; Tung, K S et al. (1995) Aod1, the immunoregulatory locus controlling abrogation of tolerance in neonatal thymectomy-induced autoimmune ovarian dysgenesis, maps to mouse chromosome 16. Proc Natl Acad Sci U S A 92:4758-62
Sudweeks, J D; Todd, J A; Blankenhorn, E P et al. (1993) Locus controlling Bordetella pertussis-induced histamine sensitization (Bphs), an autoimmune disease-susceptibility gene, maps distal to T-cell receptor beta-chain gene on mouse chromosome 6. Proc Natl Acad Sci U S A 90:3700-4
Fu, Y; Blankenhorn, E P (1992) Nitric oxide-induced anti-mitogenic effects in high and low responder rat strains. J Immunol 148:2217-22
Blankenhorn, E P; Smith, P D; Williams, C B et al. (1992) Alleles of the rat T-cell receptor beta chain gene complex. Immunogenetics 35:324-31
Williams, C B; Blankenhorn, E P; Byrd, K E et al. (1991) Organization and nucleotide sequence of the rat T cell receptor beta-chain complex. J Immunol 146:4406-13

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