Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS025738-07
Application #
2265656
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1988-02-01
Project End
1997-06-30
Budget Start
1995-07-01
Budget End
1997-06-30
Support Year
7
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Duke University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
Bartolome, J V; Wang, S; Schanberg, S M et al. (1999) Involvement of c-myc and max in CNS beta-endorphin modulation of hepatic ornithine decarboxylase responsiveness to insulin in rat pups. Life Sci 64:PL87-91
Bartolome, J V; Wang, S; Greer, N L et al. (1999) Glucocorticoid regulation of ornithine decarboxylase in the postnatal rat lung. Life Sci 64:895-904
Bartolome, J V; Alicke, B; Bartolome, M B (1997) Central administration of morphine inhibits brain and liver ornithine decarboxylase activity in neonatal rats: involvement of transcription- and non-transcription-dependent mechanisms. Eur J Pharmacol 331:145-53
Wang, S; Bartolome, J V; Schanberg, S M (1996) Neonatal deprivation of maternal touch may suppress ornithine decarboxylase via downregulation of the proto-oncogenes c-myc and max. J Neurosci 16:836-42
Bartolome, J V; Chang, K J; Bartolome, M B (1995) The inhibition of ornithine decarboxylase activity in developing rat tissues by central nervous system beta-endorphin is mediated by mu-opioid receptors, but not by delta- or epsilon-opioid receptors. Eur J Pharmacol 284:43-50
Bartolome, J V; Wang, S; Bartolome, M B (1995) Transcription-dependent and -independent regulation of hepatic ornithine decarboxylase activity by CNS beta-endorphin in rat pups. Brain Res Mol Brain Res 33:149-56
Bartolome, J V; Bartolome, M B (1994) Role of the spinal cord in intracisternal beta-endorphin-evoked suppression of liver DNA synthesis in 10-day-old rats. Brain Res 642:311-5
Bartolome, J V; Lorber, B A; Bartolome, M B (1994) Brain cholecystokinin and beta-endorphin systems may antagonistically interact to regulate tissue DNA synthesis in rat pups. Brain Res 661:19-24
Bartolome, J V; Bartolome, M B; Lorber, B A et al. (1991) Effects of central administration of beta-endorphin on brain and liver DNA synthesis in preweanling rats. Neuroscience 40:289-94
Greer, N L; Schanberg, S M; Bartolome, J V (1991) Effect of central administration of beta-endorphin on lung ornithine decarboxylase activity in developing rats. Pediatr Res 29:182-6

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