Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS026119-08
Application #
2265819
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1988-04-01
Project End
1997-03-31
Budget Start
1995-04-01
Budget End
1997-03-31
Support Year
8
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Wistar Institute
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Wiemelt, A P; Engleka, M J; Skorupa, A F et al. (1997) Immunochemical visualization and quantitation of cyclic AMP in single cells. J Biol Chem 272:31489-95
McMorris, F A; McKinnon, R D (1996) Regulation of oligodendrocyte development and CNS myelination by growth factors: prospects for therapy of demyelinating disease. Brain Pathol 6:313-29
Vemuri, G S; McMorris, F A (1996) Oligodendrocytes and their precursors require phosphatidylinositol 3-kinase signaling for survival. Development 122:2529-37
Shinar, Y; McMorris, F A (1995) Developing oligodendroglia express mRNA for insulin-like growth factor-I, a regulator of oligodendrocyte development. J Neurosci Res 42:516-27
Raible, D W; McMorris, F A (1993) Oligodendrocyte differentiation and progenitor cell proliferation are independently regulated by cyclic AMP. J Neurosci Res 34:287-94
McMorris, F A; Mozell, R L; Carson, M J et al. (1993) Regulation of oligodendrocyte development and central nervous system myelination by insulin-like growth factors. Ann N Y Acad Sci 692:321-34
Carson, M J; Behringer, R R; Brinster, R L et al. (1993) Insulin-like growth factor I increases brain growth and central nervous system myelination in transgenic mice. Neuron 10:729-40
Mozell, R L; McMorris, F A (1991) Insulin-like growth factor I stimulates oligodendrocyte development and myelination in rat brain aggregate cultures. J Neurosci Res 30:382-90
Raible, D W; McMorris, F A (1990) Induction of oligodendrocyte differentiation by activators of adenylate cyclase. J Neurosci Res 27:43-6
McMorris, F A; Furlanetto, R W; Mozell, R L et al. (1990) Regulation of oligodendrocyte development by insulin-like growth factors and cyclic nucleotides. Ann N Y Acad Sci 605:101-9

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