Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS026748-07
Application #
2266078
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1988-12-01
Project End
1997-08-31
Budget Start
1995-09-01
Budget End
1997-08-31
Support Year
7
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of California Irvine
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
161202122
City
Irvine
State
CA
Country
United States
Zip Code
92697
Bender, R A; Lauterborn, J C; Gall, C M et al. (2001) Enhanced CREB phosphorylation in immature dentate gyrus granule cells precedes neurotrophin expression and indicates a specific role of CREB in granule cell differentiation. Eur J Neurosci 13:679-86
Lauterborn, J C; Lynch, G; Vanderklish, P et al. (2000) Positive modulation of AMPA receptors increases neurotrophin expression by hippocampal and cortical neurons. J Neurosci 20:21-Aug
Elliott, R C; Gall, C M (2000) Changes in activating protein 1 (AP-1) composition correspond with the biphasic profile of nerve growth factor mRNA expression in rat hippocampus after hilus lesion-induced seizures. J Neurosci 20:2142-9
Pinkstaff, J K; Detterich, J; Lynch, G et al. (1999) Integrin subunit gene expression is regionally differentiated in adult brain. J Neurosci 19:1541-56
Pinkstaff, J K; Lynch, G; Gall, C M (1998) Localization and seizure-regulation of integrin beta 1 mRNA in adult rat brain. Brain Res Mol Brain Res 55:265-76
Lauterborn, J C; Poulsen, F R; Stinis, C T et al. (1998) Transcript-specific effects of adrenalectomy on seizure-induced BDNF expression in rat hippocampus. Brain Res Mol Brain Res 55:81-91
Conner, J M; Lauterborn, J C; Gall, C M (1998) Anterograde transport of neurotrophin proteins in the CNS--a reassessment of the neurotrophic hypothesis. Rev Neurosci 9:91-103
Kornblum, H I; Sankar, R; Shin, D H et al. (1997) Induction of brain derived neurotrophic factor mRNA by seizures in neonatal and juvenile rat brain. Brain Res Mol Brain Res 44:219-28
Gall, C M; Lauterborn, J C; Guthrie, K M et al. (1997) Seizures and the regulation of neurotrophic factor expression: associations with structural plasticity in epilepsy. Adv Neurol 72:9-24
Conner, J M; Lauterborn, J C; Yan, Q et al. (1997) Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS: evidence for anterograde axonal transport. J Neurosci 17:2295-313

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