Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS026851-06
Application #
2266161
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1988-12-01
Project End
1997-11-30
Budget Start
1995-12-15
Budget End
1996-11-30
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Colorado Denver
Department
Pharmacology
Type
Schools of Medicine
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045
Zahniser, N R; Simosky, J K; Mayfield, R D et al. (2000) Functional uncoupling of adenosine A(2A) receptors and reduced responseto caffeine in mice lacking dopamine D2 receptors. J Neurosci 20:5949-57
Mayfield, R D; Jones, B A; Miller, H A et al. (1999) Modulation of endogenous GABA release by an antagonistic adenosine A1/dopamineD1 receptor interaction in rat brain limbic regions but not basal ganglia. Synapse 33:274-81
Dayne Mayfield, R; Larson, G; Orona, R A et al. (1996) Opposing actions of adenosine A2a and dopamine D2 receptor activation on GABA release in the basal ganglia: evidence for an A2a/D2 receptor interaction in globus pallidus. Synapse 22:132-8
Mayfield, R D; Zahniser, N R (1993) Endogenous GABA release from rat striatal slices: effects of the GABAB receptor antagonist 2-hydroxy-saclofen. Synapse 14:16-23
Zahniser, N R; Cass, W A; Fitzpatrick, F A (1992) Signal transduction pathways involved in presynaptic receptor-mediated inhibition of dopamine release in rat striatum. Neurochem Int 20 Suppl:85S-88S
Hitzemann, R; Dains, K; Bier-Langing, C M et al. (1991) On the selection of mice for haloperidol response and non-response. Psychopharmacology (Berl) 103:244-50
Cass, W A; Zahniser, N R (1991) Potassium channel blockers inhibit D2 dopamine, but not A1 adenosine, receptor-mediated inhibition of striatal dopamine release. J Neurochem 57:147-52
Dunwiddie, T V; Taylor, M; Cass, W A et al. (1990) Arachidonic acid metabolites do not mediate modulation of neurotransmitter release by adenosine in rat hippocampus or striatum. Brain Res 527:76-80
Lupica, C R; Cass, W A; Zahniser, N R et al. (1990) Effects of the selective adenosine A2 receptor agonist CGS 21680 on in vitro electrophysiology, cAMP formation and dopamine release in rat hippocampus and striatum. J Pharmacol Exp Ther 252:1134-41
Cass, W A; Zahniser, N R (1990) Inhibition of striatal dopamine release by the selective D-2 dopamine receptor agonist N-0437 is blocked by quinine. Synapse 5:336-7