Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
7R01NS027849-03
Application #
3414250
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1990-01-01
Project End
1994-12-31
Budget Start
1991-07-15
Budget End
1991-12-31
Support Year
3
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Georgetown University
Department
Type
Schools of Medicine
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057
Fan, L; Yakovlev, A G; Faden, A I (1999) Site-specific cleavage of 28S rRNA as a marker of traumatic brain injury. J Neurotrauma 16:357-64
Happe, F; Brownell, H; Winner, E (1999) Acquired 'theory of mind' impairments following stroke. Cognition 70:211-40
Mukhin, A; Fan, L; Faden, A I (1996) Activation of metabotropic glutamate receptor subtype mGluR1 contributes to post-traumatic neuronal injury. J Neurosci 16:6012-20
Faden, A I (1996) Neurotoxic versus neuroprotective actions of endogenous opioid peptides: implications for treatment of CNS injury. NIDA Res Monogr 163:318-30
Headrick, J P; Faden, A I; Vink, R (1995) Intrathecal dynorphin-A infusion in rat spinal cord causes energy depletion, edema and neurologic dysfunction. Neurochem Int 26:489-95
Sun, F Y; Faden, A I (1995) Pretreatment with antisense oligodeoxynucleotides directed against the NMDA-R1 receptor enhances survival and behavioral recovery following traumatic brain injury in rats. Brain Res 693:163-8
Sun, F Y; Faden, A I (1995) Neuroprotective effects of 619C89, a use-dependent sodium channel blocker, in rat traumatic brain injury. Brain Res 673:133-40
Yakovlev, A G; Faden, A I (1995) Molecular biology of CNS injury. J Neurotrauma 12:767-77
Sun, F Y; Faden, A I (1994) High- and low-affinity NMDA receptor-binding sites in rat spinal cord: effects of traumatic injury. Brain Res 666:88-92
Headrick, J P; Bendall, M R; Faden, A I et al. (1994) Dissociation of adenosine levels from bioenergetic state in experimental brain trauma: potential role in secondary injury. J Cereb Blood Flow Metab 14:853-61

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