Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS028236-07
Application #
2266846
Study Section
Neurology A Study Section (NEUA)
Project Start
1990-01-01
Project End
1999-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Psychiatry
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Schwarcz, Robert; Guidetti, Paolo; Sathyasaikumar, Korrapati V et al. (2010) Of mice, rats and men: Revisiting the quinolinic acid hypothesis of Huntington's disease. Prog Neurobiol 90:230-45
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Lehrmann, E; Molinari, A; Speciale, C et al. (2001) Immunohistochemical visualization of newly formed quinolinate in the normal and excitotoxically lesioned rat striatum. Exp Brain Res 141:389-97
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Guidetti, P; Wu, H Q; Schwarcz, R (2000) In situ produced 7-chlorokynurenate provides protection against quinolinate- and malonate-induced neurotoxicity in the rat striatum. Exp Neurol 163:123-30
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Guidetti, P; Schwarcz, R (1999) 3-Hydroxykynurenine potentiates quinolinate but not NMDA toxicity in the rat striatum. Eur J Neurosci 11:3857-63
Hodgkins, P S; Wu, H Q; Zielke, H R et al. (1999) 2-Oxoacids regulate kynurenic acid production in the rat brain: studies in vitro and in vivo. J Neurochem 72:643-51

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