Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
3R01NS029441-05S1
Application #
2267614
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1991-04-01
Project End
1997-03-31
Budget Start
1995-04-01
Budget End
1996-03-31
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Ohio State University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210
Antony, Pierre; Freysz, Louis; Horrocks, Lloyd A et al. (2003) Ca2+-independent phospholipases A2 and production of arachidonic acid in nuclei of LA-N-1 cell cultures: a specific receptor activation mediated with retinoic acid. Brain Res Mol Brain Res 115:187-95
Antony, P; Freysz, L; Horrocks, L A et al. (2001) Effect of retinoic acid on the Ca2+-independent phospholipase A2 in nuclei of LA-N-1 neuroblastoma cells. Neurochem Res 26:83-8
Antony, P; Farooqui, A A; Horrocks, L A et al. (2001) Effect of D609 on phosphatidylcholine metabolism in the nuclei of LA-N-1 neuroblastoma cells: a key role for diacylglycerol. FEBS Lett 509:115-8
Farooqui, A A; Litsky, M L; Farooqui, T et al. (1999) Inhibitors of intracellular phospholipase A2 activity: their neurochemical effects and therapeutical importance for neurological disorders. Brain Res Bull 49:139-53
Farooqui, A A; Horrocks, L A (1999) Purification of lipases and phospholipases by heparin-sepharose chromatography. Methods Mol Biol 109:133-43
Farooqui, A A; Yang, H C; Hirashima, Y et al. (1999) Determination of plasmalogen-selective phospholipase A2 activity by radiochemical and fluorometric assay procedures. Methods Mol Biol 109:39-47
Ong, W Y; Horrocks, L A; Farooqui, A A (1999) Immunocytochemical localization of cPLA2 in rat and monkey spinal cord. J Mol Neurosci 12:123-30
Farooqui, A A; Horrocks, L A (1998) Plasmalogen-selective phospholipase A2 and its involvement in Alzheimer's disease. Biochem Soc Trans 26:243-6
Sandhya, T L; Ong, W Y; Horrocks, L A et al. (1998) A light and electron microscopic study of cytoplasmic phospholipase A2 and cyclooxygenase-2 in the hippocampus after kainate lesions. Brain Res 788:223-31
Farooqui, A A; Yang, H C; Rosenberger, T A et al. (1997) Phospholipase A2 and its role in brain tissue. J Neurochem 69:889-901

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