Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
2R01NS030485-05
Application #
2268441
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1992-04-01
Project End
1999-03-31
Budget Start
1996-04-15
Budget End
1997-03-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Bensenor, Lorena B; Kan, Ho-Man; Wang, Ningning et al. (2007) IQGAP1 regulates cell motility by linking growth factor signaling to actin assembly. J Cell Sci 120:658-69
Bloom, George S; Ren, Ke; Glabe, Charles G (2005) Cultured cell and transgenic mouse models for tau pathology linked to beta-amyloid. Biochim Biophys Acta 1739:116-24
Mateer, Scott C; Morris, Leah E; Cromer, Damond A et al. (2004) Actin filament binding by a monomeric IQGAP1 fragment with a single calponin homology domain. Cell Motil Cytoskeleton 58:231-41
Yamaoka-Tojo, Minako; Ushio-Fukai, Masuko; Hilenski, Lula et al. (2004) IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species--dependent endothelial migration and proliferation. Circ Res 95:276-83
Mateer, Scott C; Wang, Ningning; Bloom, George S (2003) IQGAPs: integrators of the cytoskeleton, cell adhesion machinery, and signaling networks. Cell Motil Cytoskeleton 55:147-55
Mateer, Scott C; McDaniel, Amanda E; Nicolas, Valerie et al. (2002) The mechanism for regulation of the F-actin binding activity of IQGAP1 by calcium/calmodulin. J Biol Chem 277:12324-33
Bloom, G S (2001) The UNC-104/KIF1 family of kinesins. Curr Opin Cell Biol 13:36-40
Bloom, G S; Goldstein, L S (1998) Cruising along microtubule highways: how membranes move through the secretory pathway. J Cell Biol 140:1277-80
Fullerton, A T; Bau, M Y; Conrad, P A et al. (1998) In vitro reconstitution of microtubule plus end-directed, GTPgammaS-sensitive motility of Golgi membranes. Mol Biol Cell 9:2699-714
Bashour, A M; Fullerton, A T; Hart, M J et al. (1997) IQGAP1, a Rac- and Cdc42-binding protein, directly binds and cross-links microfilaments. J Cell Biol 137:1555-66

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